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Revision as of 19:32, 17 June 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Acrodermatitis chronica atrophicans Microchapters

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Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Acrodermatitis chronica atrophicans from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

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Treatment

Medical Therapy

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Case #1

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Overview

Acrodermatitis chronica atrophicans is a skin rash indicative of the third or late stage of European Lyme borreliosis. It is a dermatological condition that takes a chronically progressive course and finally leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is often observed, specifically polyneuropathy.

Historical Perspective

The first record of ACA was made in 1883 in Breslau, Germany, where a physician named Alfred Buchwald first delineated it. Herxheimer and Hartmann described it in 1902 as a "tissue paper" like cutaneous atrophy.

Treatment

Medical Therapy

Treatment of ACA consists of antibiotics including doxycycline and penicillin for up to four weeks in the acute case.

References

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