Brain Stem Gliomas differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: {SR}}

Differentiating brain stem gliomas from other diseases

Brain stem gliomas must be differentiated from other diseases such as:

• Primitive neuroectodermal tumour of the CNS (Medulloblastoma, Pineoblastoma)
• Ependymoma
• Stroke
• Infection
• Demyelination (Multiple sclerosis, Guillain-Barre Syndrome, Transverse myelitis)

General imaging differential considerations include:

• Rhombencephalitis
• Acute demyelinating encephalomyelitis (ADEM)
• Neurofibromatosis type I (NF1)
• Tuberous sclerosis (TS)
• Osmotic demyelination
• Langerhans cell histiocytosis
• Hamartoma

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