Endometrial cancer classification: Difference between revisions
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:* Type 2 develops from atrophic endometrium and is not linked to hormonally driven pathogenesis. | :* Type 2 develops from atrophic endometrium and is not linked to hormonally driven pathogenesis. | ||
'''Cellular Classification of Endometrial Cancer''' | '''Cellular Classification of Endometrial Cancer''' | ||
: | : 1. Endometrioid (75%–80%).[The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant glandular epithelial elements] | ||
::* Ciliated adenocarcinoma. | ::* Ciliated adenocarcinoma. | ||
::* Secretory adenocarcinoma. | ::* Secretory adenocarcinoma. | ||
Line 20: | Line 20: | ||
: 4. Clear cell (4%). | : 4. Clear cell (4%). | ||
: 5. Squamous cell (<1%). | : 5. Squamous cell (<1%). | ||
: | : 6. Mixed (10%). | ||
: | : 7. Undifferentiated | ||
<gallery> | <gallery> |
Revision as of 15:28, 1 September 2015
Endometrial cancer Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Endometrial cancer classification On the Web |
American Roentgen Ray Society Images of Endometrial cancer classification |
Risk calculators and risk factors for Endometrial cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
- Endometrial cancers are classified in one of the following two categories:
- Type 1 may arise from complex atypical hyperplasia and is pathogenetically linked to unopposed estrogenic stimulation.
- Type 2 develops from atrophic endometrium and is not linked to hormonally driven pathogenesis.
Cellular Classification of Endometrial Cancer
- 1. Endometrioid (75%–80%).[The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant glandular epithelial elements]
- Ciliated adenocarcinoma.
- Secretory adenocarcinoma.
- Papillary or villoglandular.
- Adenocarcinoma with squamous differentiation.
- Adenoacanthoma.
- Adenosquamous.[Adenosquamous tumors contain malignant elements of both glandular and squamous epithelium]
- 2. Uterine papillary serous (<10%).
- 3. Mucinous (1%).
- 4. Clear cell (4%).
- 5. Squamous cell (<1%).
- 6. Mixed (10%).
- 7. Undifferentiated
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Endometrial stromal sarcoma
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Malignant mixed müllerian tumor