Endometrial cancer classification: Difference between revisions
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==Classification== | ==Classification== | ||
* Endometrial cancers are classified in one of the following two categories:<ref>{{Cite web | title = endometrial cancer classification | url =http://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq#section/_9 }}</ref> | * Endometrial cancers are classified in one of the following two categories:<ref>{{Cite web | title = endometrial cancer classification | url =http://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq#section/_9 }}</ref> | ||
:* Type 1 may arise from complex atypical hyperplasia and is pathogenetically linked to unopposed estrogenic stimulation. | :* Type 1 may arise from complex [[atypical hyperplasia]] and is pathogenetically linked to unopposed estrogenic stimulation. | ||
:* Type 2 develops from atrophic endometrium and is not linked to hormonally driven pathogenesis. | :* Type 2 develops from atrophic [[endometrium]] and is not linked to hormonally driven pathogenesis. | ||
'''Cellular Classification of Endometrial Cancer''' | '''Cellular Classification of Endometrial Cancer''' | ||
: 1. Endometrioid (75%–80%), (The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant glandular epithelial elements) | : 1. Endometrioid (75%–80%), (The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant [[glandular]] epithelial elements) | ||
::* Ciliated adenocarcinoma | ::* Ciliated adenocarcinoma | ||
::* Secretory adenocarcinoma | ::* Secretory adenocarcinoma | ||
::* Papillary or villoglandular | ::* [[Papillary]] or villoglandular | ||
::* Adenocarcinoma with squamous differentiation | ::* Adenocarcinoma with squamous differentiation | ||
:::* Adenoacanthoma | :::* Adenoacanthoma | ||
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: 3. Mucinous (1%) | : 3. Mucinous (1%) | ||
: 4. Clear cell (4%) | : 4. Clear cell (4%) | ||
: 5. Squamous cell (<1%) | : 5. [[Squamous cell]] (<1%) | ||
: 6. Mixed (10%) | : 6. Mixed (10%) | ||
: 7. Undifferentiated | : 7. Undifferentiated | ||
Revision as of 14:23, 2 September 2015
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Endometrial cancer classification On the Web |
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Risk calculators and risk factors for Endometrial cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Endometrial cancer may be classified according to histology into 7 subtypes: endometrioid, uterine papillary serous, mucinous, clear cell, squamous cell, mixed and undifferentiated.
Classification
- Endometrial cancers are classified in one of the following two categories:[1]
- Type 1 may arise from complex atypical hyperplasia and is pathogenetically linked to unopposed estrogenic stimulation.
- Type 2 develops from atrophic endometrium and is not linked to hormonally driven pathogenesis.
Cellular Classification of Endometrial Cancer
- 1. Endometrioid (75%–80%), (The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant glandular epithelial elements)
- Ciliated adenocarcinoma
- Secretory adenocarcinoma
- Papillary or villoglandular
- Adenocarcinoma with squamous differentiation
- Adenoacanthoma
- Adenosquamous.(Adenosquamous tumors contain malignant elements of both glandular and squamous epithelium)
- 2. Uterine papillary serous (<10%)
- 3. Mucinous (1%)
- 4. Clear cell (4%)
- 5. Squamous cell (<1%)
- 6. Mixed (10%)
- 7. Undifferentiated
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Endometrial stromal sarcoma
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Malignant mixed müllerian tumor
