Rhabdomyosarcoma laboratory findings: Difference between revisions
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==Overview== | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
When rhabdomyosarcoma is suspected, tests will be run for blood, muscle, and marrow. | When rhabdomyosarcoma is suspected, tests will be run for blood, muscle, and marrow. | ||
===Immunohistochemical marker=== | |||
Diagnosis of rhabdomyosarcoma depends on recognition of [[differentiation]] toward skeletal muscle cells. | *Diagnosis of rhabdomyosarcoma depends on recognition of [[differentiation]] toward skeletal muscle cells. | ||
*The protein '''myo D1''' is a protein normally found in developing skeletal muscle cells which disappears after the muscle matures and becomes innervated by a [[nerve]]. | |||
*Thus, '''myo D1''' is not found in normal skeletal muscle and serves as a useful immunohistochemical marker of rhabdomyosarcoma. | |||
==References== | ==References== | ||
Revision as of 15:51, 3 September 2015
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Risk calculators and risk factors for Rhabdomyosarcoma laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
When rhabdomyosarcoma is suspected, tests will be run for blood, muscle, and marrow.
Immunohistochemical marker
- Diagnosis of rhabdomyosarcoma depends on recognition of differentiation toward skeletal muscle cells.
- The protein myo D1 is a protein normally found in developing skeletal muscle cells which disappears after the muscle matures and becomes innervated by a nerve.
- Thus, myo D1 is not found in normal skeletal muscle and serves as a useful immunohistochemical marker of rhabdomyosarcoma.