Prolactinoma surgery: Difference between revisions
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==Overview== | ==Overview== | ||
Surgery is not the first-line treatment option for patients with prolactinoma. Surgery is usually reserved for patients | Surgery is not the first-line treatment option for patients with [[prolactinoma]]. [[Surgery]] is usually reserved for patients when medical therapy fails to reduce the size of the [[tumor]]. | ||
==Surgery== | ==Surgery== | ||
Revision as of 20:43, 11 September 2015
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Prolactinoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Prolactinoma surgery On the Web |
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American Roentgen Ray Society Images of Prolactinoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Surgery is not the first-line treatment option for patients with prolactinoma. Surgery is usually reserved for patients when medical therapy fails to reduce the size of the tumor.
Surgery
Surgery is indicated in patients if:
- Medical therapy cannot be tolerated
- Medical therapy fails to reduce prolactin levels
- Medical therapy fails to restore normal reproduction and pituitary function
- Medical therapy fails to reduce tumor size
If medical therapy is only partially successful, it should be continued, possibly combined with surgery or radiation.
Transsphenoidal Resection
Most often, the tumor is removed through the nasal cavity. Rarely, if the tumor is large or has spread to nearby brain tissue, the surgeon will access the tumor through an opening in the skull. The results of surgery depend on tumor size and prolactin concentrations. Surgery corrects prolactin concentrations in about 80 percent of patients with:
- Small tumors (microadenomas)
- Serum prolactin less than 200 nanograms per milliliter (ng/ml)