Glioblastoma multiforme pathophysiology: Difference between revisions
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*[[Li-Fraumeni syndrome]] | *[[Li-Fraumeni syndrome]] | ||
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* | *Ollier disease | ||
*[[Maffucci syndrome]] | *[[Maffucci syndrome]] | ||
Revision as of 22:16, 12 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Genetics
- Development of glioblastoma is the result from multiple genetic mutations.
- Genes involved in the pathogenesis of primary glioblastoma include:[1]
- Genes involved in the pathogenesis of secondary glioblastoma include:[1]
- IDH1
- p53
- Chromosomes 10q, 17p, and 19q
Associated Conditions
Glioblastoma may be associated with:[1]
Gross Pathology
Microscopic Pathology
References
- ↑ 1.0 1.1 1.2 Pathology of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma