Nasopharyngeal carcinoma overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Nasopharyngeal carcinoma''' (NPC) is a [[cancer]] originating in the [[nasopharynx]], the uppermost region of the [[pharynx]] or "throat", where the [[Nasal cavity|nasal passages]] and [[eustachian tube|auditory tubes]] join the remainder of the [[upper respiratory tract]]. NPC differs significantly from other [[head and neck cancer|cancers of the head and neck]] in its [[epidemiology|occurrence]], [[etiology|causes]], clinical behavior, and treatment. It is vastly more common in certain regions of East Asia and Africa than elsewhere, with [[virus|viral]], [[diet]]ary, and [[human genetics|genetic]] factors implicated in its causation. | '''Nasopharyngeal carcinoma''' (NPC) is a [[cancer]] originating in the [[nasopharynx]], the uppermost region of the [[pharynx]] or "throat", where the [[Nasal cavity|nasal passages]] and [[eustachian tube|auditory tubes]] join the remainder of the [[upper respiratory tract]]. NPC differs significantly from other [[head and neck cancer|cancers of the head and neck]] in its [[epidemiology|occurrence]], [[etiology|causes]], clinical behavior, and treatment. It is vastly more common in certain regions of East Asia and Africa than elsewhere, with [[virus|viral]], [[diet]]ary, and [[human genetics|genetic]] factors implicated in its causation. | ||
==Historical Perspective== | ==Historical Perspective== | ||
==Classification== | ==Classification== | ||
==Pathophysiology== | ==Pathophysiology== | ||
==Causes== | ==Causes== | ||
==Differentiating Nasopharyngeal carcinoma from other Diseases== | ==Differentiating Nasopharyngeal carcinoma from other Diseases== | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
==Risk Factors== | ==Risk Factors== | ||
Common risk factors in the development of nasopharyngeal carcinoma are Chinese (or Asian) ancestry, [[Epstein-Barr virus]] (EBV) exposure and heavy alcohol intake. | Common risk factors in the development of nasopharyngeal carcinoma are Chinese (or Asian) ancestry, [[Epstein-Barr virus]] (EBV) exposure and heavy alcohol intake. | ||
==Screening== | ==Screening== | ||
==Natural History, Complications and Prognosis== | ==Natural History, Complications and Prognosis== | ||
The common complications of nasopharyngeal carcinoma include airway obstruction, dysphagia and disfigurement of the neck or face. | The common complications of nasopharyngeal carcinoma include airway obstruction, dysphagia and disfigurement of the neck or face. | ||
==History and Symptoms== | ==History and Symptoms== | ||
==Physical Examination== | ==Physical Examination== | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
==CT== | ==CT== | ||
==MRI== | ==MRI== | ||
==Medical Therapy== | ==Medical Therapy== | ||
==Surgery== | ==Surgery== | ||
==References== | ==References== |
Revision as of 20:27, 15 September 2015
Nasopharyngeal carcinoma Microchapters |
Differentiating Nasopharyngeal carcinoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Nasopharyngeal carcinoma (NPC) is a cancer originating in the nasopharynx, the uppermost region of the pharynx or "throat", where the nasal passages and auditory tubes join the remainder of the upper respiratory tract. NPC differs significantly from other cancers of the head and neck in its occurrence, causes, clinical behavior, and treatment. It is vastly more common in certain regions of East Asia and Africa than elsewhere, with viral, dietary, and genetic factors implicated in its causation.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Nasopharyngeal carcinoma from other Diseases
Epidemiology and Demographics
Risk Factors
Common risk factors in the development of nasopharyngeal carcinoma are Chinese (or Asian) ancestry, Epstein-Barr virus (EBV) exposure and heavy alcohol intake.
Screening
Natural History, Complications and Prognosis
The common complications of nasopharyngeal carcinoma include airway obstruction, dysphagia and disfigurement of the neck or face.