Nasopharyngeal carcinoma other diagnostic studies: Difference between revisions
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***Abundant dense eosinophilic cytoplasm | ***Abundant dense eosinophilic cytoplasm | ||
***Central nuclei +/- small/indistinct nucleoli | ***Central nuclei +/- small/indistinct nucleoli | ||
[[ | [[ | ||
Image:Lymphoepithelioma_met_to_LN_6.jpg |thumb|none|250px| Nasopharyngeal carcinoma]] | |||
==Immunohistochemistry== | |||
*EBER +ve | |||
*p16 -ve<ref name=pmid9546345>{{cite journal |author=Gulley ML, Nicholls JM, Schneider BG, Amin MB, Ro JY, Geradts J |title=Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product |journal=Am. J. Pathol. |volume=152 |issue=4 |pages=865–9 |year=1998 |month=April |pmid=9546345 |pmc=1858242 |doi= |url=}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 17:30, 17 September 2015
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Nasopharyngeal carcinoma Microchapters |
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Differentiating Nasopharyngeal carcinoma from other Diseases |
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Diagnosis |
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Risk calculators and risk factors for Nasopharyngeal carcinoma other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Biopsy may be helpful in the diagnosis of nasopharyngeal carcinoma.
Other Diagnostic Studies
Biopsy may be helpful in the diagnosis of nasopharyngeal carcinoma.
Biopsy Findings
Microscopic Features:[1]
- Prominent lymphoid component - key feature
- Features of squamous cell carcinoma:
- Cohesive cells with:
- Abundant dense eosinophilic cytoplasm
- Central nuclei +/- small/indistinct nucleoli
- Cohesive cells with:
[[
Image:Lymphoepithelioma_met_to_LN_6.jpg |thumb|none|250px| Nasopharyngeal carcinoma]]
Immunohistochemistry
- EBER +ve
- p16 -ve[2]
References
- ↑ Nasopharyngeal carcinoma http://librepathology.org/wiki/index.php/Nasopharyngeal_carcinoma
- ↑ Gulley ML, Nicholls JM, Schneider BG, Amin MB, Ro JY, Geradts J (1998). "Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product". Am. J. Pathol. 152 (4): 865–9. PMC 1858242. PMID 9546345. Unknown parameter
|month=ignored (help)