Endometrial cancer classification: Difference between revisions
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==Classification== | ==Classification== | ||
===Classification Based on Pathogenesis=== | |||
* Endometrial cancers are classified into either type 1 or type 2:<ref>{{Cite web | title = endometrial cancer classification | url =http://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq#section/_9 }}</ref> | * Endometrial cancers are classified into either type 1 or type 2:<ref>{{Cite web | title = endometrial cancer classification | url =http://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq#section/_9 }}</ref> | ||
:* Type 1 may arise from complex atypical [[hyperplasia]] and is pathogenetically linked to unopposed estrogenic stimulation. | :* Type 1 may arise from complex atypical [[hyperplasia]] and is pathogenetically linked to unopposed estrogenic stimulation. | ||
:* Type 2 develops from atrophic [[endometrium]] and is not linked to hormonally driven pathogenesis. | :* Type 2 develops from atrophic [[endometrium]] and is not linked to hormonally driven pathogenesis. | ||
===Classification Based on Histopathological Subtype=== | |||
: 1. Endometrioid (75%–80%)(The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant [[glandular]] epithelial elements) | : 1. Endometrioid (75%–80%)(The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant [[glandular]] epithelial elements) | ||
::* Ciliated adenocarcinoma | ::* Ciliated adenocarcinoma | ||
Revision as of 02:52, 22 September 2015
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Endometrial cancer Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Endometrial cancer classification On the Web |
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American Roentgen Ray Society Images of Endometrial cancer classification |
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Risk calculators and risk factors for Endometrial cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
Endometrial cancer may be classified according to histology into 7 subtypes: endometrioid, uterine papillary serous, mucinous, clear cell, squamous cell, mixed and undifferentiated.
Classification
Classification Based on Pathogenesis
- Endometrial cancers are classified into either type 1 or type 2:[1]
- Type 1 may arise from complex atypical hyperplasia and is pathogenetically linked to unopposed estrogenic stimulation.
- Type 2 develops from atrophic endometrium and is not linked to hormonally driven pathogenesis.
Classification Based on Histopathological Subtype
- 1. Endometrioid (75%–80%)(The most common endometrial cancer cell type is endometrioid adenocarcinoma, which is composed of malignant glandular epithelial elements)
- Ciliated adenocarcinoma
- Secretory adenocarcinoma
- Papillary or villoglandular
- Adenocarcinoma with squamous differentiation
- Adenoacanthoma
- Adenosquamous (Adenosquamous tumors contain malignant elements of both glandular and squamous epithelium)
- 2. Uterine papillary serous (<10%)
- 3. Mucinous (1%)
- 4. Clear cell (4%)
- 5. Squamous cell (<1%)
- 6. Mixed (10%)
- 7. Undifferentiated