Rhabdomyosarcoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

According to the Children's Oncology Group, there are four stages of rhabdomyosarcoma based on the location of tumor, size of tumor, involvement of lymph nodes, and metastasis.

Staging of rhabdomyosarcoma

According to the Children's Oncology Group, there are four stages of rhabdomyosarcoma based on the location of tumor, size of tumor, involvement of lymph nodes, and metastasis. The stages of rhabdomyosarcoma are shown in the table below:

Staging system for rhabdomyosarcoma

Stage	Description
Stage 1	Favorable site- orbit, eyelid, head and neck (excluding parameningeal), genitourinary (non-bladder, non-prostate); N0 or N1; M0
Stage 2	Unfavorable site- urinary bladder, prostate, extremity, trunk, parameningeal, other; size <5 cm; N0; M0
Stage 3	Unfavorable site- Bladder, prostate, extremity, trunk, parameningeal, other; size <5 cm; N1; M0
Stage 3	Unfavorable site- Bladder, prostate, extremity, trunk, parameningeal, other; size >5 cm; N0 or N1; M0
Stage 4	Favorable or unfavorable site- N0 or N1 ; M1

^{N0 = Regional nodes not clinically involved; N1 = Regional nodes clinically involved; M0 = No metastasis; M1 = distant metastasis}