Insulinoma epidemiology and demographics: Difference between revisions
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==Epidemiology== | ==Epidemiology== | ||
Insulinomas are rare [[neuroendocrine tumor]]s with an incidence estimated at 1 to 4 new cases per million persons per year. Insulinoma is one of the most common types of | *Insulinomas are rare [[neuroendocrine tumor]]s with an incidence estimated at 1 to 4 new cases per million persons per year. | ||
*Insulinoma is one of the most common types of tumor arising from the [[islets of Langerhans]] cells (pancreatic endocrine tumors). | |||
*Estimates of malignancy (metastases) range from 5% to 30%. | |||
The median age at diagnosis is 47 years. | *Over 99% of insulinomas originate in the pancreas, with rare cases from ectopic pancreatic tissue. | ||
Females are more commonly affected with insulinoma than males. The male to female ratio is approximately 2 to 3. | *About 5% of cases are associated with tumors of the parathyroid glands and the pituitary ([[Multiple endocrine neoplasia type 1]]) and are more likely to be multiple and malignant. | ||
There is no racial predilection to the insulinoma. | *Most insulinomas are small, less than 2 cm.</br> | ||
*The median age at diagnosis is 47 years. | |||
*Females are more commonly affected with insulinoma than males. The male to female ratio is approximately 2 to 3. | |||
*There is no racial predilection to the insulinoma. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:50, 1 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Epidemiology
- Insulinomas are rare neuroendocrine tumors with an incidence estimated at 1 to 4 new cases per million persons per year.
- Insulinoma is one of the most common types of tumor arising from the islets of Langerhans cells (pancreatic endocrine tumors).
- Estimates of malignancy (metastases) range from 5% to 30%.
- Over 99% of insulinomas originate in the pancreas, with rare cases from ectopic pancreatic tissue.
- About 5% of cases are associated with tumors of the parathyroid glands and the pituitary (Multiple endocrine neoplasia type 1) and are more likely to be multiple and malignant.
- Most insulinomas are small, less than 2 cm.
- The median age at diagnosis is 47 years.
- Females are more commonly affected with insulinoma than males. The male to female ratio is approximately 2 to 3.
- There is no racial predilection to the insulinoma.