Gliomatosis cerebri MRI: Difference between revisions

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Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by bilateral and diffuse infiltrative tumor which is isointense or hypointense on T1-weighted images and hyperintense on T2-weighted and FLAIR images.<ref name=ddd>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid9075253">{{cite journal| author=Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z et al.| title=A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation. | journal=Pediatr Neurosurg | year= 1996 | volume= 25 | issue= 2 | pages= 94-9 | pmid=9075253 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9075253  }} </ref>
Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by bilateral and diffuse infiltrative tumor which is isointense or hypointense on T1-weighted images and hyperintense on T2-weighted and FLAIR images.<ref name=ddd>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid9075253">{{cite journal| author=Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z et al.| title=A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation. | journal=Pediatr Neurosurg | year= 1996 | volume= 25 | issue= 2 | pages= 94-9 | pmid=9075253 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9075253  }} </ref>
==MRI==
==MRI==
Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by bilateral and diffuse infiltrative tumor which is isointense or hypointense on T1-weighted images and hyperintense on T2-weighted and FLAIR images.<ref name=ddd>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid9075253">{{cite journal| author=Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z et al.| title=A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation. | journal=Pediatr Neurosurg | year= 1996 | volume= 25 | issue= 2 | pages= 94-9 | pmid=9075253 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9075253  }} </ref>
Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by:<ref name=ddd>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid9075253">{{cite journal| author=Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z et al.| title=A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation. | journal=Pediatr Neurosurg | year= 1996 | volume= 25 | issue= 2 | pages= 94-9 | pmid=9075253 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9075253  }} </ref>


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*No restriction
*No restriction
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MR spectroscopy
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*E​levated [[choline]]/[[creatine]] and [[choline]]/NAA ratios
*Marked elevation of myo-inositol
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MR perfusion
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*​Low/normal rCBV
*Correlates with no vascular hyperplasia
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Revision as of 17:49, 5 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by bilateral and diffuse infiltrative tumor which is isointense or hypointense on T1-weighted images and hyperintense on T2-weighted and FLAIR images.[1][2]

MRI

Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by:[1][2]

MRI component Findings

T1

  • Iso to hypointense to grey matter

T2

  • Hyperintense to grey matter

T1C+

  • No or minimal enhancement

DWI

  • No restriction



  • Axial FLAIR gliomatosis cerebri MRI.[3]
    Axial FLAIR gliomatosis cerebri MRI.[3]
  • T1 MRI of gliomatosis cerebri.[3]
    T1 MRI of gliomatosis cerebri.[3]
  • Coronal T2 gliomatosis cerebri MRI.[3]
    Coronal T2 gliomatosis cerebri MRI.[3]
  • T2 MRI of gliomatosis cerebri.[3]
    T2 MRI of gliomatosis cerebri.[3]
  • Axial T1 MRI of gliomatosis cerebri.[3]
    Axial T1 MRI of gliomatosis cerebri.[3]
  • Axial ADC of gliomatosis cerebri.[3]
    Axial ADC of gliomatosis cerebri.[3]
  • MR spectroscopy of gliomatosis cerebri.[3]
    MR spectroscopy of gliomatosis cerebri.[3]

References

  1. ↑ 1.0 1.1 Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri
  2. ↑ 2.0 2.1 Onal C, Bayindir C, Siraneci R, Izgi N, Yalçin I, Altinel Z; et al. (1996). "A serial CT scan and MRI verification of diffuse cerebrospinal gliomatosis: a case report with stereotactic diagnosis and radiological confirmation". Pediatr Neurosurg. 25 (2): 94–9. PMID 9075253.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Image courtesy of Dr. Henry Knipe and Dr. Frank Gaillard et al. Radiopaedia (original file here').Creative Commons BY-SA-NC


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