Insulinoma overview: Difference between revisions
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==Overview== | ==Overview== | ||
An '''insulinoma''' is a [[tumour]] of the [[pancreas]] derived from the [[beta cell]]s which while retaining the ability to synthesize and secrete [[insulin]] is autonomous of the normal feedback mechanisms. Patients present with symptomatic [[hypoglycemia]] which is ameliorated by feeding. The diagnosis of an insulinoma is usually made biochemically with low blood sugar, elevated insulin, pro-insulin and C-peptide levels and confirmed by [[medical imaging]] or angiography. The definitive treatment is surgery. | An '''insulinoma''' is a [[tumour]] of the [[pancreas]] derived from the [[beta cell]]s which while retaining the ability to synthesize and secrete [[insulin]] is autonomous of the normal feedback mechanisms. Patients present with symptomatic [[hypoglycemia]] which is ameliorated by feeding. The diagnosis of an insulinoma is usually made biochemically with low blood sugar, elevated insulin, pro-insulin and C-peptide levels and confirmed by [[medical imaging]] or angiography. The definitive treatment is surgery. | ||
==Historical Perspective== | |||
==Pathogenesis== | |||
==Causes== | |||
==Differential Diagnosis== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Natural History, Complications and Prognosis== | |||
==Staging== | |||
==History and Symptoms== | |||
==Physical Examination== | |||
==Laboratory Findings== | |||
==CT== | |||
==MRI== | |||
==Ultrasonography== | |||
==Other Imaging Findings== | |||
==Other Diagnostic Findings== | |||
==Medical Therapy== | |||
==Surgery== | |||
==Primary Prevention== | |||
==Secondary Prevention== | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 21:45, 7 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
An insulinoma is a tumour of the pancreas derived from the beta cells which while retaining the ability to synthesize and secrete insulin is autonomous of the normal feedback mechanisms. Patients present with symptomatic hypoglycemia which is ameliorated by feeding. The diagnosis of an insulinoma is usually made biochemically with low blood sugar, elevated insulin, pro-insulin and C-peptide levels and confirmed by medical imaging or angiography. The definitive treatment is surgery.