Oligoastrocytoma pathophysiology

Oligoastrocytoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Pathophysiology

Genetics

• Genes associated with the pathogenesis of oligoastrocytoma include:

• IDH1
• t(1;19)(q10;p10)
• p53

Gross Pathology

• On gross pathology, oligoastrocytoma is characterized by

Microscopic Pathology

On microscopic histopathological analysis, oligoastrocytoma is characterized by:

On microscopic histopathological analysis, anaplastic oligoastrocytoma is characterized by:

Immunohistochemistry

Oligoastrocytoma is demonstrated by positivity to tumor markers such as:

• MAP2
• GFAP
• Ki-67
• IDH1

References

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