Hairy cell leukemia classification: Difference between revisions
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{{Hairy cell leukemia}} | {{Hairy cell leukemia}} | ||
{{CMG}} | {{CMG}} {{AE}}{{HL}} | ||
==Overview== | ==Overview== | ||
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* '''Occurs in approximately 95% of the cases'''<br> | * '''Occurs in approximately 95% of the cases'''<br> | ||
* '''The male to female ratio is approximately 4 to 1'''<br> | * '''The male to female ratio is approximately<br> 4 to 1'''<br> | ||
* '''The median age at diagnosis is 55 years'''<br> | * '''The median age at diagnosis is 55 years'''<br> | ||
* '''Less than 10% lymphocytosis on peripheral blood smear'''<br> | * '''Less than 10% lymphocytosis on peripheral blood smear'''<br> | ||
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* '''Occurs in approximately 5% of the cases'''<br> | * '''Occurs in approximately 5% of the cases'''<br> | ||
* '''The male to female ratio is approximately 2 to 1'''<br> | * '''The male to female ratio is approximately<br> 2 to 1'''<br> | ||
* '''The median age at diagnosis is greater than 70 years'''<br> | * '''The median age at diagnosis is greater than 70 years'''<br> | ||
* '''greater than 90% lymphocytosis on peripheral blood smear'''<br> | * '''greater than 90% lymphocytosis on peripheral blood smear'''<br> | ||
Revision as of 20:21, 19 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
- Hairy cell leukemia may be classified into two subtypes: Hairy cell leukemia (classic) and hairy cell leukemia variant.[1]
Classification
- Hairy cell leukemia may be classified into two subtypes: Hairy cell leukemia (classic) and hairy cell leukemia variant.[1]
- Hairy cell leukemia variant is still considered a provisional entity at this time, as the WHO is unable to recognize it as distinct diseases due to insufficient evidence.[2]
- The algorithm below illustrates characteristic findings associated with each subtypes:[3]
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Hairy cell leukemia | Hairy cell leukemia variant | ||||||||||||||||||||||||||||||||||||||||||
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References
- ↑ 1.0 1.1 Hairy cell leukemia. Wikipedia (2015) https://en.wikipedia.org/wiki/Hairy_cell_leukemia#Classification Accessed on October, 17 2015
- ↑ Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES (2011). "The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications". Blood. 117 (19): 5019–32. doi:10.1182/blood-2011-01-293050. PMC 3109529. PMID 21300984.
- ↑ Matutes E (2006). "Immunophenotyping and differential diagnosis of hairy cell leukemia". Hematol Oncol Clin North Am. 20 (5): 1051–63. doi:10.1016/j.hoc.2006.06.012. PMID 16990106.