Hepatoblastoma risk factors: Difference between revisions

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Revision as of 13:42, 28 October 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

The table below lists risk factors for hepatoblastoma:^[1]


Associated Disorder	Clinical findings

Aicardi syndrome	Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies.
Beckwith-Wiedemann syndrome	Hemihypertrophy, hemihyperplasia.
Familial adenomatous polyposis
Glycogen storage diseases I–IV	Symptoms vary by individual disorder.
Low-birth-weight infants	Preterm and small-for-gestation-age neonates.
Simpson-Golabi-Behmel syndrome	Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of Wilms tumor.
Trisomy 18, other trisomies	Trisomy 18: Microcephaly and micrognathia, clenched fists with overlapping fingers, and failure to thrive. Most patients (>90%) die in the first month of life.

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-|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Trisomy 18, other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" |
+|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Trisomy 18]], other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" |
 :*[[Trisomy 18]]: [[Microcephaly]] and [[micrognathia]], clenched fists with overlapping fingers, and failure to thrive. Most patients (>90%) die in the first month of life.