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==Overview==
==Overview==
Laryngeal cancer may also be called '''cancer of the larynx''' or '''laryngeal carcinoma'''.  Most laryngeal cancers are [[squamous cell carcinoma]]s, reflecting their origin from the [[squamous cell]]s which form the majority of the laryngeal [[epithelium]]. [[Cancer]] can develop in any part of the [[larynx]], but the cure rate is affected by the location of the tumor. For the purposes of tumour [[Cancer staging|staging]], the larynx is divided into three anatomical regions: the [[glottis]] (true vocal cords, anterior and posterior commissures); the supraglottis ([[epiglottis]], [[arytenoids]] and [[aryepiglottic folds]], and [[Vocal folds#False vocal folds|false cords]]); the subglottis. Most laryngeal cancers originate in the [[glottis]]. Supraglottic cancers are less common, and subglottic tumours are least frequent.Laryngeal cancer may spread, either by direct extension to adjacent structures, by [[metastasis]] to regional cervical [[lymph node]]s or more distantly, through the blood stream. Distant metastates to the lung are most common.  
Most laryngeal cancers are [[squamous cell carcinoma]]s, reflecting their origin from the [[squamous cell]]s which form the majority of the laryngeal [[epithelium]]. [[Cancer]] can develop in any part of the [[larynx]], but the cure rate is affected by the location of the tumor. For the purposes of tumor [[Cancer staging|staging]], the larynx is divided into three anatomical regions: the [[glottis]] (true vocal cords, anterior and posterior commissures); the supraglottis ([[epiglottis]], [[arytenoids]] and [[aryepiglottic folds]], and [[Vocal folds#False vocal folds|false cords]]); the subglottis. Most laryngeal cancers originate in the [[glottis]]. Supraglottic cancers are less common, and subglottic tumors are least frequent.Laryngeal cancer may spread, either by direct extension to adjacent structures, by [[metastasis]] to regional cervical [[lymph node]]s or more distantly, through the blood stream. Distant metastates to the lung are most common.


==Historical Perspective==
==Historical Perspective==

Revision as of 19:56, 28 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

Most laryngeal cancers are squamous cell carcinomas, reflecting their origin from the squamous cells which form the majority of the laryngeal epithelium. Cancer can develop in any part of the larynx, but the cure rate is affected by the location of the tumor. For the purposes of tumor staging, the larynx is divided into three anatomical regions: the glottis (true vocal cords, anterior and posterior commissures); the supraglottis (epiglottis, arytenoids and aryepiglottic folds, and false cords); the subglottis. Most laryngeal cancers originate in the glottis. Supraglottic cancers are less common, and subglottic tumors are least frequent.Laryngeal cancer may spread, either by direct extension to adjacent structures, by metastasis to regional cervical lymph nodes or more distantly, through the blood stream. Distant metastates to the lung are most common.

Historical Perspective

Pathophysiology

Causes

Differentiating Laryngeal cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

References


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