Cholangiocarcinoma classification: Difference between revisions

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Revision as of 13:50, 29 October 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

Classification

Cholangiocarcinoma may be classified according to location of the tumor into 3 subtypes:

Extrahepatic bile duct cancer
Perihilar bile duct cancer
Intrahepatic bile duct cancer

Cellular Classification of Cholangiocarcinoma

Extrahepatic Bile Duct Cancer

Carcinoma in situ
Adenocarcinoma, not otherwise specified (NOS)
Adenocarcinoma

Intestinal type
Mucinous type
Clear cell type

Signet-ring cell carcinoma
Adenosquamous carcinoma
Squamous cell carcinoma
Small cell (oat cell) carcinoma
Undifferentiated carcinoma

Spindle cell type
Giant cell type
Small cell type

Papillomatosis
Papillary carcinoma

Noninvasive

Papillary carcinoma
Invasive
Carcinoma, NOS

Perihilar Bile Duct Cancer The histologic types include the following:

Carcinoma in situ
Adenocarcinoma, not otherwise specified (NOS)
Adenocarcinoma:*Intestinal type

Mucinous type
Clear cell type

Signet-ring cell carcinoma
Adenosquamous carcinoma
Squamous cell carcinoma
Small cell (oat cell) carcinoma
Undifferentiated carcinoma

Spindle cell type:*Giant cell type
Small cell type

Papillomatosis
Papillary carcinoma:*Noninvasive
Papillary carcinoma*:Invasive
Carcinoma, NOS

Intrahepatic Bile Duct Cancer

Mass-forming tumor growth pattern
Periductal-infiltrating tumor growth pattern
Mixed mass-forming and periductal-infiltrating growth pattern

References

@@ Line 5: / Line 5: @@
 ==Classification==
 Cholangiocarcinoma may be classified according to location of the tumor into 3 subtypes:
-*Extrahepatic Bile Duct Cancer
+*Extrahepatic bile duct cancer
-*Perihilar Bile Duct Cancer
+*Perihilar bile duct cancer
-*Intrahepatic Bile Duct Cancer
+*Intrahepatic bile duct cancer
 ===Cellular Classification of Cholangiocarcinoma===
 '''Extrahepatic Bile Duct Cancer'''
-Adenocarcinomas are the most common type of extrahepatic bile duct tumors. The histologic subtypes include:
 *Carcinoma in situ
 *Adenocarcinoma, not otherwise specified (NOS)
-*Adenocarcinoma, intestinal type
+*Adenocarcinoma
-*Mucinous adenocarcinoma
+:*Intestinal type
-*Clear cell adenocarcinoma
+:*Mucinous type
+:*Clear cell type
 *Signet-ring cell carcinoma
 *Adenosquamous carcinoma
@@ Line 21: / Line 22: @@
 *Small cell (oat cell) carcinoma
 *Undifferentiated carcinoma
-:*Spindle and giant cell types
+:*Spindle cell type
-:*Small cell types
+:*Giant cell type
+:*Small cell type
 *Papillomatosis
-*Papillary carcinoma, noninvasive
+*Papillary carcinoma
-*Papillary carcinoma, invasive
+:*Noninvasive
+*Papillary carcinoma
+*:Invasive
 *Carcinoma, NOS
 '''Perihilar Bile Duct Cancer'''
-Adenocarcinomas are the most common type of perihilar bile duct tumors. The histologic types include the following:
+The histologic types include the following:
+*Carcinoma in situ
-Carcinoma in situ.
+*Adenocarcinoma, not otherwise specified (NOS)
-Adenocarcinoma, not otherwise specified (NOS).
+*Adenocarcinoma:*Intestinal type
-Adenocarcinoma, intestinal type.
+:*Mucinous type
-Mucinous adenocarcinoma.
+:*Clear cell type
-Clear cell adenocarcinoma.
+*Signet-ring cell carcinoma
-Signet-ring cell carcinoma.
+*Adenosquamous carcinoma
-Adenosquamous carcinoma.
+*Squamous cell carcinoma
-Squamous cell carcinoma.
+*Small cell (oat cell) carcinoma
-Small cell (oat cell) carcinoma.
+*Undifferentiated carcinoma
-Undifferentiated carcinoma
+:*Spindle cell type:*Giant cell type
+:*Small cell type
-Spindle and giant cell types.
+*Papillomatosis
-Small cell types.
+*Papillary carcinoma:*Noninvasive
+*Papillary carcinoma*:Invasive
-Papillomatosis.
+*Carcinoma, NOS
-Papillary carcinoma, noninvasive.
-Papillary carcinoma, invasive.
-Carcinoma, NOS
-Intrahepatic Bile Duct Cancer
-The most common histologic types of intrahepatic bile duct tumors include the following:
-Intrahepatic cholangiocarcinoma.
-Mass-forming tumor growth pattern.
-Periductal-infiltrating tumor growth pattern.
-Mixed mass-forming and periductal-infiltrating growth pattern.
-Mixed hepatocellular.
+'''Intrahepatic Bile Duct Cancer'''
+:*Mass-forming tumor growth pattern
+:*Periductal-infiltrating tumor growth pattern
+:*Mixed mass-forming and periductal-infiltrating growth pattern
 ==References==