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==Overview==
==Overview==
==Classification==
==Classification==
Cholangiocarcinoma may be classified according to location of the tumor into 3 subtypes:<ref>{{cite journal |author=KLATSKIN G |title=ADENOCARCINOMA OF THE HEPATIC DUCT AT ITS BIFURCATION WITHIN THE PORTA HEPATIS. AN UNUSUAL TUMOR WITH DISTINCTIVE CLINICAL AND PATHOLOGICAL FEATURES |journal=Am J Med |volume=38 |issue= |pages=241-56 |year= |pmid=14256720}}</ref>  
Cholangiocarcinoma may be classified according to location of the tumor into three subtypes:<ref>{{cite journal |author=KLATSKIN G |title=ADENOCARCINOMA OF THE HEPATIC DUCT AT ITS BIFURCATION WITHIN THE PORTA HEPATIS. AN UNUSUAL TUMOR WITH DISTINCTIVE CLINICAL AND PATHOLOGICAL FEATURES |journal=Am J Med |volume=38 |issue= |pages=241-56 |year= |pmid=14256720}}</ref>  


*Extrahepatic bile duct cancer
*Extrahepatic bile duct cancer

Revision as of 18:38, 29 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

Classification

Cholangiocarcinoma may be classified according to location of the tumor into three subtypes:[1]

  • Extrahepatic bile duct cancer
  • Perihilar bile duct cancer
  • Intrahepatic bile duct cancer

Cellular Classification of Cholangiocarcinoma

Extrahepatic Bile Duct Cancer

  • Carcinoma in situ
  • Adenocarcinoma, not otherwise specified (NOS)
  • Adenocarcinoma
  • Intestinal type
  • Mucinous type
  • Clear cell type
  • Signet-ring cell carcinoma
  • Adenosquamous carcinoma
  • Squamous cell carcinoma
  • Small cell (oat cell) carcinoma
  • Undifferentiated carcinoma
  • Spindle cell type
  • Giant cell type
  • Small cell type
  • Papillomatosis
  • Papillary carcinoma
  • Noninvasive
  • Papillary carcinoma
    Invasive
  • Carcinoma, NOS

Perihilar Bile Duct Cancer The histologic types include the following:

  • Carcinoma in situ
  • Adenocarcinoma, not otherwise specified (NOS)
  • Adenocarcinoma:*Intestinal type
  • Mucinous type
  • Clear cell type
  • Signet-ring cell carcinoma
  • Adenosquamous carcinoma
  • Squamous cell carcinoma
  • Small cell (oat cell) carcinoma
  • Undifferentiated carcinoma
  • Spindle cell type:*Giant cell type
  • Small cell type
  • Papillomatosis
  • Papillary carcinoma:*Noninvasive
  • Papillary carcinoma*:Invasive
  • Carcinoma, NOS

Intrahepatic Bile Duct Cancer

  • Mass-forming tumor growth pattern
  • Periductal-infiltrating tumor growth pattern
  • Mixed mass-forming and periductal-infiltrating growth pattern

References

  1. KLATSKIN G. "ADENOCARCINOMA OF THE HEPATIC DUCT AT ITS BIFURCATION WITHIN THE PORTA HEPATIS. AN UNUSUAL TUMOR WITH DISTINCTIVE CLINICAL AND PATHOLOGICAL FEATURES". Am J Med. 38: 241–56. PMID 14256720.