Hepatoblastoma pathophysiology: Difference between revisions
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===Genetic=== | ===Genetic=== | ||
Genes involved in the pathogenesis of hepatoblastoma include:<ref name="JiaDong2014">{{cite journal|last1=Jia|first1=Deshui|last2=Dong|first2=Rui|last3=Jing|first3=Ying|last4=Xu|first4=Dan|last5=Wang|first5=Qifeng|last6=Chen|first6=Lei|last7=Li|first7=Qigen|last8=Huang|first8=Yuping|last9=Zhang|first9=Yuannv|last10=Zhang|first10=Zhenfeng|last11=Liu|first11=Li|last12=Zheng|first12=Shan|last13=Xia|first13=Qiang|last14=Wang|first14=Hongyang|last15=Dong|first15=Kuiran|last16=He|first16=Xianghuo|title=Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex|journal=Hepatology|volume=60|issue=5|year=2014|pages=1686–1696|issn=02709139|doi=10.1002/hep.27243}}</ref> | Genes involved in the pathogenesis of hepatoblastoma include:<ref name="JiaDong2014">{{cite journal|last1=Jia|first1=Deshui|last2=Dong|first2=Rui|last3=Jing|first3=Ying|last4=Xu|first4=Dan|last5=Wang|first5=Qifeng|last6=Chen|first6=Lei|last7=Li|first7=Qigen|last8=Huang|first8=Yuping|last9=Zhang|first9=Yuannv|last10=Zhang|first10=Zhenfeng|last11=Liu|first11=Li|last12=Zheng|first12=Shan|last13=Xia|first13=Qiang|last14=Wang|first14=Hongyang|last15=Dong|first15=Kuiran|last16=He|first16=Xianghuo|title=Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex|journal=Hepatology|volume=60|issue=5|year=2014|pages=1686–1696|issn=02709139|doi=10.1002/hep.27243}}</ref> | ||
* ''CTNNB1'' | |||
* ''CAPRIN2'' | |||
* ''SPOP'' | |||
* ''OR5I1'' | |||
* ''CDC20B'' | |||
==Gross Pathology== | ==Gross Pathology== | ||
==Microscopic Pathology== | ==Microscopic Pathology== |
Revision as of 14:33, 3 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Pathophysiology
Genetic
Genes involved in the pathogenesis of hepatoblastoma include:[1]
- CTNNB1
- CAPRIN2
- SPOP
- OR5I1
- CDC20B
Gross Pathology
Microscopic Pathology
References
- ↑ Jia, Deshui; Dong, Rui; Jing, Ying; Xu, Dan; Wang, Qifeng; Chen, Lei; Li, Qigen; Huang, Yuping; Zhang, Yuannv; Zhang, Zhenfeng; Liu, Li; Zheng, Shan; Xia, Qiang; Wang, Hongyang; Dong, Kuiran; He, Xianghuo (2014). "Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex". Hepatology. 60 (5): 1686–1696. doi:10.1002/hep.27243. ISSN 0270-9139.