Hepatoblastoma pathophysiology: Difference between revisions
Jump to navigation
Jump to search
Nawal Muazam (talk | contribs) No edit summary |
Nawal Muazam (talk | contribs) No edit summary |
||
| Line 14: | Line 14: | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
On microscopic histopathological analysis, hepatoblastoma is characterized by: | On microscopic histopathological analysis, hepatoblastoma is characterized by: | ||
* Small round cell | * Small round cell tumor | ||
* Fetal hepatocytes ~ 1:3 NC ratio, eosinophilic cytoplasm | * Fetal hepatocytes ~ 1:3 NC ratio, eosinophilic cytoplasm | ||
* +/- Mesenchymal component | * +/- Mesenchymal component | ||
** Immature fibrous tissue, osteoid or cartilage | ** Immature fibrous tissue, osteoid or cartilage | ||
==References== | ==References== | ||
{{reflist|1}} | {{reflist|1}} | ||
Revision as of 15:32, 3 November 2015
|
Hepatoblastoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Hepatoblastoma pathophysiology On the Web |
|
American Roentgen Ray Society Images of Hepatoblastoma pathophysiology |
|
Risk calculators and risk factors for Hepatoblastoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Pathophysiology
Genetics
Genes involved in the pathogenesis of hepatoblastoma include:[1]
Gross Pathology
Microscopic Pathology
On microscopic histopathological analysis, hepatoblastoma is characterized by:
- Small round cell tumor
- Fetal hepatocytes ~ 1:3 NC ratio, eosinophilic cytoplasm
- +/- Mesenchymal component
- Immature fibrous tissue, osteoid or cartilage
References
- ↑ Jia, Deshui; Dong, Rui; Jing, Ying; Xu, Dan; Wang, Qifeng; Chen, Lei; Li, Qigen; Huang, Yuping; Zhang, Yuannv; Zhang, Zhenfeng; Liu, Li; Zheng, Shan; Xia, Qiang; Wang, Hongyang; Dong, Kuiran; He, Xianghuo (2014). "Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex". Hepatology. 60 (5): 1686–1696. doi:10.1002/hep.27243. ISSN 0270-9139.