Hepatoblastoma natural history: Difference between revisions
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==Natural History== | ==Natural History== | ||
==Complications== | ==Complications== | ||
Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include: | Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include:<ref name="MadabhaviPatel2014">{{cite journal|last1=Madabhavi|first1=Irappa|last2=Patel|first2=Apurva|last3=Choudhary|first3=Mukesh|last4=Aagre|first4=Suhas|last5=Revannasiddaiah|first5=Swaroop|last6=Modi|first6=Gaurang|last7=Anand|first7=Asha|last8=Panchal|first8=Harsha|last9=Parikh|first9=Sonia|last10=Raut|first10=Shreeniwas|title=Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity|journal=Case Reports in Pediatrics|volume=2014|year=2014|pages=1–5|issn=2090-6803|doi=10.1155/2014/104543}}</ref> | ||
* Erythrocytosis | * Erythrocytosis | ||
* Thrombocytosis | * Thrombocytosis | ||
Revision as of 14:43, 4 November 2015
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Hepatoblastoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hepatoblastoma natural history On the Web |
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American Roentgen Ray Society Images of Hepatoblastoma natural history |
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Risk calculators and risk factors for Hepatoblastoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2] Nawal Muazam M.D.[3]
Overview
Natural History
Complications
Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include:[1]
- Erythrocytosis
- Thrombocytosis
- Hypocalcaemia
- Isosexual precocious puberty
- Hypoglycaemia
Prognosis
- The 5-year survival rate of children with hepatoblastoma is approximately 70%.[2]
- The table below lists prognosis of hepatoblastma based on staging:[3]
| Subtype | Description |
|---|---|
| Stage I |
|
| Stage II |
|
| Stage III |
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| Stage IV |
|
Factors that Affect Prognosis (chance of recovery) and Treatment Options
- The 5-year survival rate of children with hepatoblastoma is approximately 70%.
- The prognosis (chance of recovery) and treatment options depend on the following:
- The stage of the cancer (the size of the tumor
- Whether it affects part or all of the liver
- Whether it has spread to other places in the body, such as the lungs).
- Whether the cancer can be removed completely by surgery.
- The type of liver cancer (hepatoblastoma or hepatocellular).
- Whether the cancer has just been diagnosed or has recurred.
- Prognosis may also depend on:
- Certain features of the cancer cell (determined microscopically).
- Whether the AFP blood levels go down after chemotherapy is initiated.
References
- ↑ Madabhavi, Irappa; Patel, Apurva; Choudhary, Mukesh; Aagre, Suhas; Revannasiddaiah, Swaroop; Modi, Gaurang; Anand, Asha; Panchal, Harsha; Parikh, Sonia; Raut, Shreeniwas (2014). "Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity". Case Reports in Pediatrics. 2014: 1–5. doi:10.1155/2014/104543. ISSN 2090-6803.
- ↑ Prognosis and Prognostic Factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015
- ↑ Treatment and prognosis of hepatoblastoma. Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/hepatoblastoma. Accessed on November 3, 2015