Salivary gland tumor pathophysiology: Difference between revisions
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| style="padding: 5px 5px; background: #F5F5F5;" |Occasionally encapsulated, mixed proportion of glandular, myoepithelial and mesenchymal cells | | style="padding: 5px 5px; background: #F5F5F5;" |Occasionally encapsulated, mixed proportion of glandular, myoepithelial and mesenchymal cells | ||
|- | |- | ||
| style="padding: 5px 5px; background: # | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Warthin tumor | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Papillary, bilayer | | style="padding: 5px 5px; background: #F5F5F5;" |Papillary, bilayer | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Cuboid (basal), columnar (apical) | | style="padding: 5px 5px; background: #F5F5F5;" |Cuboid (basal), columnar (apical) | ||
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| style="padding: 5px 5px; background: #F5F5F5;" |AKA papillary cystadenoma lymphomatosum | | style="padding: 5px 5px; background: #F5F5F5;" |AKA papillary cystadenoma lymphomatosum | ||
|- | |- | ||
| style="padding: 5px 5px; background: # | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Basal cell adenoma | ||
| style="padding: 5px 5px; background: #F5F5F5;" |variable, islands surrounded by hyaline bands, lesion encapsulated | | style="padding: 5px 5px; background: #F5F5F5;" |variable, islands surrounded by hyaline bands, lesion encapsulated | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Basaloid | | style="padding: 5px 5px; background: #F5F5F5;" |Basaloid | ||
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| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
|- | |- | ||
| style="padding: 5px 5px; background: # | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Canalicular adenoma | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Chains of cells | | style="padding: 5px 5px; background: #F5F5F5;" |Chains of cells | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Cuboid or columnar | | style="padding: 5px 5px; background: #F5F5F5;" |Cuboid or columnar | ||
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| style="padding: 5px 5px; background: #F5F5F5;" |Exclusively oral cavity, 80% in upper lip; immunohistochemistry: p63- | | style="padding: 5px 5px; background: #F5F5F5;" |Exclusively oral cavity, 80% in upper lip; immunohistochemistry: p63- | ||
|- | |- | ||
| style="padding: 5px 5px; background: # | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Sialoblastoma | ||
| style="padding: 5px 5px; background: #F5F5F5;" |variable, islands surrounded by loose fibrous stroma | | style="padding: 5px 5px; background: #F5F5F5;" |variable, islands surrounded by loose fibrous stroma | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Basaloid | | style="padding: 5px 5px; background: #F5F5F5;" |Basaloid |
Revision as of 04:15, 8 November 2015
Salivary gland tumor Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
The pathophysiology of salivary gland tumors depends on the histological subtype.
Pathophysiology
Entity | Architecture | Morphology | Cell borders | Cytoplasm | Nucleus | Differential Diagnosis | Other |
---|---|---|---|---|---|---|---|
Pleomorphic adenoma | Variable | mixed proportion; must include:
|
Variable | Variable | Plasmacytoid | Adenoid cystic carcinoma | Occasionally encapsulated, mixed proportion of glandular, myoepithelial and mesenchymal cells |
Warthin tumor | Papillary, bilayer | Cuboid (basal), columnar (apical) | Clearly seen | Eosinophilic, abundant | Unremarkable | Sebaceous lymphadenoma | AKA papillary cystadenoma lymphomatosum |
Basal cell adenoma | variable, islands surrounded by hyaline bands, lesion encapsulated | Basaloid | Subtle | Scant, hyperchromatic | Granular | Basal cell adenocarcinoma | |
Canalicular adenoma | Chains of cells | Cuboid or columnar | Subtle | Scant, hyperchromatic | Granular | Basal cell adenoma | Exclusively oral cavity, 80% in upper lip; immunohistochemistry: p63- |
Sialoblastoma | variable, islands surrounded by loose fibrous stroma | Basaloid | Subtle | Scant, hyperchromatic | Granular | Adenoid cystic carcinoma | Basal cell adenocarcinoma |