Cholangiocarcinoma history and symptoms: Difference between revisions
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The most common symptom of cholangiocarcinoma is [[jaundice]] (yellowing of the eyes and skin), which occurs when bile ducts are blocked by the tumor. To some extent, the symptoms depend upon the location of the tumor. Patients with cholangiocarcinoma in the extrahepatic bile ducts (outside the liver) are more likely to have jaundice, while those with tumors of the [[bile ducts]] within the liver often have pain without jaundice.<ref name="nakeeb">{{cite journal |author=Nakeeb A, Pitt H, Sohn T, Coleman J, Abrams R, Piantadosi S, Hruban R, Lillemoe K, Yeo C, Cameron J |title=Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors |journal=Ann Surg |volume=224 |issue=4 |pages=463–73; discussion 473-5 |year=1996 |id=PMID 8857851}}</ref>Other common symptoms include, in order of frequency:<ref>{{cite journal |author=Nagorney D, Donohue J, Farnell M, Schleck C, Ilstrup D |title=Outcomes after curative resetions of cholangiocarcinoma |journal=Arch Surg |volume=128 |issue=8 |pages=871–7; discussion 877-9 |year=1993 |id=PMID 8393652}}</ref> | The most common symptom of cholangiocarcinoma is [[jaundice]] (yellowing of the eyes and skin), which occurs when bile ducts are blocked by the tumor. To some extent, the symptoms depend upon the location of the tumor. Patients with cholangiocarcinoma in the extrahepatic bile ducts (outside the liver) are more likely to have jaundice, while those with tumors of the [[bile ducts]] within the liver often have pain without jaundice.<ref name="nakeeb">{{cite journal |author=Nakeeb A, Pitt H, Sohn T, Coleman J, Abrams R, Piantadosi S, Hruban R, Lillemoe K, Yeo C, Cameron J |title=Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors |journal=Ann Surg |volume=224 |issue=4 |pages=463–73; discussion 473-5 |year=1996 |id=PMID 8857851}}</ref>Other common symptoms include, in order of frequency:<ref>{{cite journal |author=Nagorney D, Donohue J, Farnell M, Schleck C, Ilstrup D |title=Outcomes after curative resetions of cholangiocarcinoma |journal=Arch Surg |volume=128 |issue=8 |pages=871–7; discussion 877-9 |year=1993 |id=PMID 8393652}}</ref> | ||
*[[pruritis|Generalized itching]] (66%) | *[[pruritis|Generalized itching]] (66%) | ||
*[[Abdominal pain]] (30% to 50%) | *[[Abdominal pain]] (30% to 50%) | ||
*[[Weight loss]] (30% to 50%) | *[[Weight loss]] (30% to 50%) | ||
*[[Fever]] (up to 20%) | *[[Fever]] (up to 20%) | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
The common symptoms of cholangiocarcinoma include jaundice, pruritis, abdominal pain, weight loss, fatigue, and loss of appetite
Symptoms
The most common symptom of cholangiocarcinoma is jaundice (yellowing of the eyes and skin), which occurs when bile ducts are blocked by the tumor. To some extent, the symptoms depend upon the location of the tumor. Patients with cholangiocarcinoma in the extrahepatic bile ducts (outside the liver) are more likely to have jaundice, while those with tumors of the bile ducts within the liver often have pain without jaundice.[1]Other common symptoms include, in order of frequency:[2]
- Generalized itching (66%)
- Abdominal pain (30% to 50%)
- Weight loss (30% to 50%)
- Fever (up to 20%)
- Fatigue
- Loss of appetite
-
Yellowing of the skin and eyes (jaundice)
References
- ↑ Nakeeb A, Pitt H, Sohn T, Coleman J, Abrams R, Piantadosi S, Hruban R, Lillemoe K, Yeo C, Cameron J (1996). "Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors". Ann Surg. 224 (4): 463–73, discussion 473-5. PMID 8857851.
- ↑ Nagorney D, Donohue J, Farnell M, Schleck C, Ilstrup D (1993). "Outcomes after curative resetions of cholangiocarcinoma". Arch Surg. 128 (8): 871–7, discussion 877-9. PMID 8393652.