Salivary gland tumor medical therapy: Difference between revisions
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==References== | ==References== |
Revision as of 21:46, 10 November 2015
Salivary gland tumor Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Salivary gland tumor medical therapy On the Web |
American Roentgen Ray Society Images of Salivary gland tumor medical therapy |
Risk calculators and risk factors for Salivary gland tumor medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Stage | Grade | Treatment |
---|---|---|
Stage I major salivary gland cancer | Low-grade tumors | Surgery alone |
Postoperative radiation therapy should be considered when the resection margins are positive | ||
High-grade tumors | Localized high-grade salivary gland tumors that are confined to the gland in which they arise may be cured by radical surgery alone | |
Postoperative radiation therapy may improve local control and increase survival rates for patients with high-grade tumors, positive surgical margins, or perineural invasion | ||
Stage II major salivary gland cancer | Low-grade tumors | Surgery alone or with postoperative radiation therapy, if indicated, is appropriate |
Chemotherapy should be considered in special circumstances, such as when radiation therapy or surgery is refused | ||
HIgh-grade tumors | Localized high-grade salivary gland tumors that are confined to the gland in which they arise may be cured by radical surgery alone | |
Postoperative radiation therapy may improve local control and increase survival rates for patients with high-grade tumors, positive surgical margins, or perineural invasion | ||
Fast neutron-beam radiation therapy or accelerated hyperfractionated photon-beam schedules reportedly are more effective than conventional x-ray therapy in the treatment of patients with inoperable, unresectable, or recurrent malignant salivary gland tumors | ||
Stage III major salivary gland cancer | Low-grade tumors | Surgery alone or with postoperative radiation therapy, if indicated, is appropriate. |
Chemotherapy should be considered in special circumstances, such as when radiation or surgery is refused or when tumors are recurrent or nonresponsive | ||
High-grade tumors | Patients with localized high-grade salivary gland tumors that are confined to the gland in which they arise may be cured by radical surgery alone | |
Postoperative radiation therapy may improve local control and increase survival rates for patients with high-grade tumors, positive surgical margins, or perineural invasion | ||
Fast neutron-beam radiation therapy or accelerated hyperfractionated photon-beam schedules have been reported to be more effective than conventional x-ray therapy in the treatment of patients with inoperable, unresectable, or recurrent malignant salivary gland tumors | ||
Stage IV major salivary gland cancer | Standard therapy for patients with tumors that have spread to distant sites is not curative | Fast neutron-beam radiation therapy or accelerated hyperfractionated photon-beam schedules have been reported to be more effective than conventional x-ray therapy in the treatment of patients with inoperable, unresectable, or recurrent malignant salivary gland tumors |
Recurrent major salivary gland cancer | Fast neutron-beam radiation therapy is superior to conventional radiation therapy using x-rays and may be curative in selected patients with recurrent disease |