Hamartoma overview: Difference between revisions
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== | ==Overview== | ||
A '''hamartoma''' (from Greek hamartion “bodily defect”) is a focal [[malformation]] that resembles a [[neoplasm]] in the tissue of its origin. This is not a [[malignant]] tumor, and it grows at the same rate as the surrounding [[tissues]]. It is composed of tissue elements normally found at that site but that are growing in a disorganized fashion.<ref> Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 147. ISBN 978-1416054542.</ref>They occur in many different parts of the body and are most often asymptomatic and undetected unless seen on an image taken for another reason ([[incidentaloma]]). | A '''hamartoma''' (from Greek hamartion “bodily defect”) is a focal [[malformation]] that resembles a [[neoplasm]] in the tissue of its origin. This is not a [[malignant]] tumor, and it grows at the same rate as the surrounding [[tissues]]. It is composed of tissue elements normally found at that site but that are growing in a disorganized fashion.<ref> Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 147. ISBN 978-1416054542.</ref>They occur in many different parts of the body and are most often asymptomatic and undetected unless seen on an image taken for another reason ([[incidentaloma]]). | ||
== | ==Historical Perspective== | ||
== | ==Classification== | ||
== | ==Pathophysiology== | ||
==Causes== | |||
Hamartomas may be caused by an abnormal formation of normal tissue.<ref name=wiki> Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015</ref> | Hamartomas may be caused by an abnormal formation of normal tissue.<ref name=wiki> Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015</ref> | ||
== | ==Differential diagnosis== | ||
== | ==Epidemiology and Demographics== | ||
== | ==Risk Factors== | ||
== | ==Screening== | ||
== | ==Natural History, Complications and Prognosis== | ||
If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer. Common complications of hamartomas will depend on the location and size. Prognosis is generally regraded as excellent.<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref> | If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer. Common complications of hamartomas will depend on the location and size. Prognosis is generally regraded as excellent.<ref name="pmid15615988">{{cite journal |vauthors=Marchiori E, Souza AS, Franquet T, Müller NL |title=Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT |journal=AJR Am J Roentgenol |volume=184 |issue=1 |pages=273–82 |year=2005 |pmid=15615988 |doi=10.2214/ajr.184.1.01840273 |url=}}</ref> | ||
== Diagnosis == | == Diagnosis == | ||
===Staging=== | |||
===History and Symptoms=== | |||
===Physical examination=== | |||
===Laboratory tests=== | |||
===Chest X-ray=== | |||
===CT=== | |||
===MRI=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical therapy=== | |||
===Surgery=== | |||
==References== | ==References== | ||
Revision as of 16:23, 8 December 2015
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American Roentgen Ray Society Images of Hamartoma overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
A hamartoma (from Greek hamartion “bodily defect”) is a focal malformation that resembles a neoplasm in the tissue of its origin. This is not a malignant tumor, and it grows at the same rate as the surrounding tissues. It is composed of tissue elements normally found at that site but that are growing in a disorganized fashion.[1]They occur in many different parts of the body and are most often asymptomatic and undetected unless seen on an image taken for another reason (incidentaloma).
Historical Perspective
Classification
Pathophysiology
Causes
Hamartomas may be caused by an abnormal formation of normal tissue.[2]
Differential diagnosis
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer. Common complications of hamartomas will depend on the location and size. Prognosis is generally regraded as excellent.[3]
Diagnosis
Staging
History and Symptoms
Physical examination
Laboratory tests
Chest X-ray
CT
MRI
Other Diagnostic Studies
Treatment
Medical therapy
Surgery
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 147. ISBN 978-1416054542.
- ↑ Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015
- ↑ Marchiori E, Souza AS, Franquet T, Müller NL (2005). "Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT". AJR Am J Roentgenol. 184 (1): 273–82. doi:10.2214/ajr.184.1.01840273. PMID 15615988.