Thymic carcinoma surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Surgery is the mainstay of treatment for thymic carcinoma.

Surgery

Treatment options for thymic carcinoma include the following:

• Surgery
• Radiation
• Cisplatin-based chemotherapy

• For patients with clinically resectable disease, surgical resection is often the initial therapeutic intervention.
• For clinically borderline or frankly unresectable lesions, neoadjuvant (preoperative) chemotherapy or thoracic radiation therapy, or both, is given.
• Patients presenting with locally advanced disease should be carefully evaluated and undergo multimodality therapy.
• Patients with poor performance status and high associated operative risks are generally not considered for these types of aggressive treatments.
• Patients with metastatic disease may respond to combination chemotherapy.