Chancroid natural history, complications and prognosis: Difference between revisions
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*In approximately 25% of patients with lymphadenitis, lymph nodes may swell to form fluctuant [[Bubo|buboes]]. Untreated buboes may rupture, discharge exudate, and ulcerate.<ref name="Lewis2003"></ref> | *In approximately 25% of patients with lymphadenitis, lymph nodes may swell to form fluctuant [[Bubo|buboes]]. Untreated buboes may rupture, discharge exudate, and ulcerate.<ref name="Lewis2003"></ref> | ||
*Chancroid is not lethal. | *Chancroid is not lethal. | ||
==Complications== | |||
*Coinfection with [[Human Immunodeficiency Virus (HIV)|HIV]]: | |||
::''H. ducreyi'' facilitates infection of HIV | |||
::Presence of HIV may result in atypical manifestations of chancroid including: increased number of lesions, extragenital lesions, delayed treatment response<ref name="ChancroidUpToDate"></ref> | |||
*Coinfection with [[syphilis]] | |||
*[[Phimosis]] in men | |||
==References== | ==References== | ||
Revision as of 15:45, 20 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Nate Michalak, B.A.; Serge Korjian M.D.
Overview
Natural History
- The incubation period for H. ducreyi is typically 4 to 10 days, after which erythematous papules arise.[1]
- Approximately 2 to 3 days after symptom onset, papules evolve into pustules.[2]
- Pustules may resolve spontaneously or ulcerate in approximately 1-2 weeks since formation. Patients typically develop between 1-4 ulcers.
- Inguinal lymphadenitis develops in approximately half of patients, usually unilaterally and more commonly in males than females, 1 to 2 weeks after appearance of primary ulcer.[3]
- In approximately 25% of patients with lymphadenitis, lymph nodes may swell to form fluctuant buboes. Untreated buboes may rupture, discharge exudate, and ulcerate.[3]
- Chancroid is not lethal.
Complications
- Coinfection with HIV:
- H. ducreyi facilitates infection of HIV
- Presence of HIV may result in atypical manifestations of chancroid including: increased number of lesions, extragenital lesions, delayed treatment response[1]
References
- ↑ 1.0 1.1 Chancroid. UpToDate (September 25, 2015). http://www.uptodate.com/contents/chancroid#H3 Accessed January 19, 2016.
- ↑ Spinola, S. M. (2002). "Immunopathogenesis of Haemophilus ducreyi Infection (Chancroid)". Infection and Immunity. 70 (4): 1667–1676. doi:10.1128/IAI.70.4.1667-1676.2002. ISSN 0019-9567.
- ↑ 3.0 3.1 Lewis, D A (2003). "Chancroid: clinical manifestations, diagnosis, and management". Sexually Transmitted Infections. 79 (1): 68–71. doi:10.1136/sti.79.1.68. ISSN 1368-4973.