Colorado tick fever pathophysiology: Difference between revisions
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{{CMG}} {{AE}} {{IMD}} | {{CMG}} {{AE}} {{IMD}} | ||
==Overview== | ==Overview== | ||
Colorado tick fever is an Orbivirus or | Colorado tick fever is an [[Orbivirus]] or [[Coltivirus]] that chronically infects Rocky Mountain wood ticks. The virus typically infects cells in [[bone marrow]] causing issues with the development of certain [[Blood cell|blood cells]]. Infection is transmitted by the bite of an infected Rocky Mountain wood tick. | ||
==Viral classification== | ==Viral classification== | ||
*Genera of Colorado tick fever is wither an Orbivirus or Coltivirus. | *Genera of Colorado tick fever is wither an Orbivirus or Coltivirus. | ||
*Four serotypes are responsible for human infections.<ref name= "CTF book"> Rotaviruses, Reoviruses, Coltiviruses, and Orbiviruses. http://www.ncbi.nlm.nih.gov/books/NBK8558/ 1996; Accessed January 21, 2016. </ref> | *Four [[serotypes]] are responsible for human infections.<ref name="CTF book">Rotaviruses, Reoviruses, Coltiviruses, and Orbiviruses. http://www.ncbi.nlm.nih.gov/books/NBK8558/ 1996; Accessed January 21, 2016. </ref> | ||
==Pathogenesis== | ==Pathogenesis== | ||
*Viral pathway involves targeting the cells in bone marrow or young child's central nervous system. | *Viral pathway involves targeting the cells in bone marrow or young child's [[central nervous system]]. | ||
*Inhibits the proper development of blood cells. | *Inhibits the proper development of blood cells. | ||
*A host defense mechanism, humoral immunity, is elicited by infection.<ref name= "CTF book"> Rotaviruses, Reoviruses, Coltiviruses, and Orbiviruses. http://www.ncbi.nlm.nih.gov/books/NBK8558/ 1996; Accessed January 21, 2016. </ref> | *A host defense mechanism, [[humoral immunity]], is elicited by infection.<ref name="CTF book">Rotaviruses, Reoviruses, Coltiviruses, and Orbiviruses. http://www.ncbi.nlm.nih.gov/books/NBK8558/ 1996; Accessed January 21, 2016. </ref> | ||
==Transmission== | ==Transmission== | ||
*Infection with Colorado tick fever occurs as a result of being bitten by an infected Rocky Mountain wood tick (Dermacentor andersoni). | *Infection with Colorado tick fever occurs as a result of being bitten by an infected Rocky Mountain wood tick ([[Dermacentor andersoni|Dermacentor andersoni).]] | ||
*Colorado tick fever is transmitted to a tick during a blood meal involving a rodent reservoir such as a squirrels, chipmunks, and mice. | *Colorado tick fever is transmitted to a tick during a blood meal involving a rodent reservoir such as a squirrels, chipmunks, and mice. | ||
*Infection perpetuates as a tick continues to feed on another host. | *Infection perpetuates as a tick continues to feed on another host. | ||
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[[Image:Ctf-lifecycle.jpg|600px|left|thumb|The Colorado tick fever life cycle.<ref> Centers for Disease and Control, Colorado tick fever transmission. http://www.cdc.gov/coloradotickfever/transmission.html Accessed January 20,2016 </ref>]] | [[Image:Ctf-lifecycle.jpg|600px|left|thumb|The Colorado tick fever life cycle.<ref>Centers for Disease and Control, Colorado tick fever transmission. http://www.cdc.gov/coloradotickfever/transmission.html Accessed January 20,2016 </ref>]] | ||
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Revision as of 20:21, 2 February 2016
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Colorado tick fever Microchapters |
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Colorado tick fever pathophysiology On the Web |
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American Roentgen Ray Society Images of Colorado tick fever pathophysiology |
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Risk calculators and risk factors for Colorado tick fever pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ilan Dock, B.S.
Overview
Colorado tick fever is an Orbivirus or Coltivirus that chronically infects Rocky Mountain wood ticks. The virus typically infects cells in bone marrow causing issues with the development of certain blood cells. Infection is transmitted by the bite of an infected Rocky Mountain wood tick.
Viral classification
- Genera of Colorado tick fever is wither an Orbivirus or Coltivirus.
- Four serotypes are responsible for human infections.[1]
Pathogenesis
- Viral pathway involves targeting the cells in bone marrow or young child's central nervous system.
- Inhibits the proper development of blood cells.
- A host defense mechanism, humoral immunity, is elicited by infection.[1]
Transmission
- Infection with Colorado tick fever occurs as a result of being bitten by an infected Rocky Mountain wood tick (Dermacentor andersoni).
- Colorado tick fever is transmitted to a tick during a blood meal involving a rodent reservoir such as a squirrels, chipmunks, and mice.
- Infection perpetuates as a tick continues to feed on another host.
- Viral transmission from human to human is rare, however may occur during blood transfusion.
References
- ↑ 1.0 1.1 Rotaviruses, Reoviruses, Coltiviruses, and Orbiviruses. http://www.ncbi.nlm.nih.gov/books/NBK8558/ 1996; Accessed January 21, 2016.
- ↑ Centers for Disease and Control, Colorado tick fever transmission. http://www.cdc.gov/coloradotickfever/transmission.html Accessed January 20,2016