Aspergillosis history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} {{HL}} | {{CMG}}; {{AE}} {{HL}} | ||
==Overview== | ==Overview== | ||
==History== | ==History== | ||
* When evaluating a patient for aspergillosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough occupational history. Other specific areas of focus when obtaining the history are outlined below:<ref name="mayo">Aspergillosis. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/aspergillosis/basics/risk-factors/con-20030330 Accessed on February, 8 2016</ref><ref name="pmid21881144">{{cite journal| author=Kousha M, Tadi R, Soubani AO| title=Pulmonary aspergillosis: a clinical review. | journal=Eur Respir Rev | year= 2011 | volume= 20 | issue= 121 | pages= 156-74 | pmid=21881144 | doi=10.1183/09059180.00001011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21881144 }} </ref> | * When evaluating a patient for aspergillosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough occupational history. Other specific areas of focus when obtaining the history are outlined below:<ref name="mayo">Aspergillosis. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/aspergillosis/basics/risk-factors/con-20030330 Accessed on February, 8 2016</ref><ref name="pmid21881144">{{cite journal| author=Kousha M, Tadi R, Soubani AO| title=Pulmonary aspergillosis: a clinical review. | journal=Eur Respir Rev | year= 2011 | volume= 20 | issue= 121 | pages= 156-74 | pmid=21881144 | doi=10.1183/09059180.00001011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21881144 }} </ref> | ||
:* Review past medical history for any previous immunodeficient states such as AIDS, hematological cancers, and cystic fibrosis | :* Review past medical history for any previous immunodeficient states such as [[AIDS]], hematological cancers, and [[cystic fibrosis]] | ||
:* Review past medical history for any previous cavitary pulmonary disease such as tuberculosis or sarcoidosis, which may predispose to aspergilloma formation | :* Review past medical history for any previous cavitary [[pulmonary]] disease such as [[tuberculosis]] or [[sarcoidosis]], which may predispose to aspergilloma formation | ||
:* Review surgical history for any organ transplantation procedures | :* Review surgical history for any organ transplantation procedures | ||
:* Patients medications review for any immune-suppressive drugs such as chemotherapy and long term corticosteroid use | :* Patients medications review for any immune-suppressive drugs such as [[chemotherapy]] and long term [[corticosteroid]] use | ||
==Symptoms== | ==Symptoms== | ||
* The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as: | * The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as: | ||
:* '''Invasive pulmonary aspergillosis''' may present with: | :* '''Invasive pulmonary aspergillosis''' may present with: | ||
::* Spiking [fever]] (refractory to [[antibiotic]] therapy) | ::* Spiking [[fever]] (refractory to [[antibiotic]] therapy) | ||
::* [[Pleuritic]] [[chest pain]] | ::* [[Pleuritic]] [[chest pain]] | ||
::* [[Cough]] | ::* [[Cough]] | ||
| Line 38: | Line 33: | ||
::* [[Dyspnea]] | ::* [[Dyspnea]] | ||
::* Fever (related to bacterial super-infection) | ::* Fever (related to bacterial super-infection) | ||
:* '''Allergic bronchopulmonary aspergillosis'' ('''ABPA''') may present with: | :* '''Allergic bronchopulmonary aspergillosis''' ('''ABPA''') may present with: | ||
::* [[Wheezing]] | ::* [[Wheezing]] | ||
::* [[Cough]] | ::* [[Cough]] | ||
Revision as of 17:07, 8 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
History
- When evaluating a patient for aspergillosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough occupational history. Other specific areas of focus when obtaining the history are outlined below:[1][2]
- Review past medical history for any previous immunodeficient states such as AIDS, hematological cancers, and cystic fibrosis
- Review past medical history for any previous cavitary pulmonary disease such as tuberculosis or sarcoidosis, which may predispose to aspergilloma formation
- Review surgical history for any organ transplantation procedures
- Patients medications review for any immune-suppressive drugs such as chemotherapy and long term corticosteroid use
Symptoms
- The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as:
- Invasive pulmonary aspergillosis may present with:
- Spiking fever (refractory to antibiotic therapy)
- Pleuritic chest pain
- Cough
- Shortness of breath
- Haemoptysis
- Headache
- Seizures
- Chronic necrotizing aspergillosis may present with:
- Chronic fever (1-6 months)
- Malaise
- Fatigue
- Weight loss
- Chronic productive cough
- Haemoptysis (may be severe)
- Aspergilloma may present with:
- Most patients with aspergilloma are asymptomatic
- Mild haemoptysis (most common symptom)
- Cough
- Dyspnea
- Fever (related to bacterial super-infection)
- Allergic bronchopulmonary aspergillosis (ABPA) may present with:
References
- ↑ Aspergillosis. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/aspergillosis/basics/risk-factors/con-20030330 Accessed on February, 8 2016
- ↑ Kousha M, Tadi R, Soubani AO (2011). "Pulmonary aspergillosis: a clinical review". Eur Respir Rev. 20 (121): 156–74. doi:10.1183/09059180.00001011. PMID 21881144.