Aspergillosis history and symptoms: Difference between revisions
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==Symptoms== | ==Symptoms== | ||
* The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as:<ref name="mayo">Aspergillosis. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/aspergillosis/basics/risk-factors/con-20030330 Accessed on February, 8 2016</ref><ref name="pmid21881144">{{cite journal| author=Kousha M, Tadi R, Soubani AO| title=Pulmonary aspergillosis: a clinical review. | journal=Eur Respir Rev | year= 2011 | volume= 20 | issue= 121 | pages= 156-74 | pmid=21881144 | doi=10.1183/09059180.00001011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21881144 }} </ref> | * The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as:<ref name="mayo">Aspergillosis. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/aspergillosis/basics/risk-factors/con-20030330 Accessed on February, 8 2016</ref><ref name="pmid21881144">{{cite journal| author=Kousha M, Tadi R, Soubani AO| title=Pulmonary aspergillosis: a clinical review. | journal=Eur Respir Rev | year= 2011 | volume= 20 | issue= 121 | pages= 156-74 | pmid=21881144 | doi=10.1183/09059180.00001011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21881144 }} </ref> | ||
===Invasive Pulmonary Aspergillosis=== | |||
::* Spiking [[fever]] (refractory to [[antibiotic]] therapy) | ::* Spiking [[fever]] (refractory to [[antibiotic]] therapy) | ||
::* [[Pleuritic]] [[chest pain]] | ::* [[Pleuritic]] [[chest pain]] | ||
| Line 20: | Line 20: | ||
::* [[Headache]] | ::* [[Headache]] | ||
::* [[Seizures]] | ::* [[Seizures]] | ||
===Chronic Necrotizing Aspergillosis= | |||
::* Chronic [[fever]] (1-6 months) | ::* Chronic [[fever]] (1-6 months) | ||
::* [[Malaise]] | ::* [[Malaise]] | ||
| Line 27: | Line 27: | ||
::* Chronic productive [[cough]] | ::* Chronic productive [[cough]] | ||
::* [[Haemoptysis]] (may be severe) | ::* [[Haemoptysis]] (may be severe) | ||
===Aspergilloma=== | |||
::* Most patients with aspergilloma are asymptomatic | ::* Most patients with aspergilloma are asymptomatic | ||
::* Mild [[haemoptysis]] (most common symptom) | ::* Mild [[haemoptysis]] (most common symptom) | ||
| Line 33: | Line 33: | ||
::* [[Dyspnea]] | ::* [[Dyspnea]] | ||
::* Fever (related to bacterial super-infection) | ::* Fever (related to bacterial super-infection) | ||
===Allergic Bronchopulmonary Aspergillosis (ABPA)=== | |||
::* [[Wheezing]] | ::* [[Wheezing]] | ||
::* [[Cough]] | ::* [[Cough]] | ||
| Line 43: | Line 43: | ||
[[Category:Fungal diseases]] | [[Category:Fungal diseases]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
Revision as of 21:12, 8 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as:[1][2] Symptoms of invasive pulmonary aspergillosis include spiking fever, pleuritic chest pain, cough, and dyspnea. Symptoms of chronic necrotizing aspergillosis include chronic fever, weight loss, productive cough, and haemoptysis. Most patients with aspergilloma are asymptomatic.
History
- When evaluating a patient for aspergillosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough occupational history. Other specific areas of focus when obtaining the history are outlined below:[1][2]
- Review past medical history for any previous immunodeficient states such as AIDS, hematological cancers, and cystic fibrosis
- Review past medical history for any previous cavitary pulmonary disease such as tuberculosis or sarcoidosis, which may predispose to aspergilloma formation
- Review surgical history for any organ transplantation procedures
- Patients medications review for any immune-suppressive drugs such as chemotherapy and long term corticosteroid use
Symptoms
- The specific clinical presentation of aspergillosis is determined by the exact clinical subtype of the disease such as:[1][2]
Invasive Pulmonary Aspergillosis
- Spiking fever (refractory to antibiotic therapy)
- Pleuritic chest pain
- Cough
- Dyspnea
- Haemoptysis
- Headache
- Seizures
==Chronic Necrotizing Aspergillosis
- Chronic fever (1-6 months)
- Malaise
- Fatigue
- Weight loss
- Chronic productive cough
- Haemoptysis (may be severe)
Aspergilloma
- Most patients with aspergilloma are asymptomatic
- Mild haemoptysis (most common symptom)
- Cough
- Dyspnea
- Fever (related to bacterial super-infection)
Allergic Bronchopulmonary Aspergillosis (ABPA)
References
- ↑ 1.0 1.1 1.2 Aspergillosis. MAYO CLINIC (2015) http://www.mayoclinic.org/diseases-conditions/aspergillosis/basics/risk-factors/con-20030330 Accessed on February, 8 2016
- ↑ 2.0 2.1 2.2 Kousha M, Tadi R, Soubani AO (2011). "Pulmonary aspergillosis: a clinical review". Eur Respir Rev. 20 (121): 156–74. doi:10.1183/09059180.00001011. PMID 21881144.