Aspergillosis other diagnostic studies: Difference between revisions
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===PCR=== | ===PCR=== | ||
A single negative PCR result is enough to exclude a diagnosis of a probable invasive aspergillosis.<ref name="pmid19179225">{{cite journal| author=Mengoli C, Cruciani M, Barnes RA, Loeffler J, Donnelly JP| title=Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis. | journal=Lancet Infect Dis | year= 2009 | volume= 9 | issue= 2 | pages= 89-96 | pmid=19179225 | doi=10.1016/S1473-3099(09)70019-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19179225 }} </ref> | * A single negative PCR result is enough to exclude a diagnosis of a probable invasive aspergillosis.<ref name="pmid19179225">{{cite journal| author=Mengoli C, Cruciani M, Barnes RA, Loeffler J, Donnelly JP| title=Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis. | journal=Lancet Infect Dis | year= 2009 | volume= 9 | issue= 2 | pages= 89-96 | pmid=19179225 | doi=10.1016/S1473-3099(09)70019-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19179225 }} </ref> | ||
While, two positive test results are required to confirm a diagnosis of aspergillosis. | * While, two positive test results are required to confirm a diagnosis of aspergillosis. | ||
==Gallery== | ==Gallery== | ||
Revision as of 22:33, 8 February 2016
Aspergillosis Microchapters |
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Treatment |
Case Studies |
Aspergillosis other diagnostic studies On the Web |
American Roentgen Ray Society Images of Aspergillosis other diagnostic studies |
Risk calculators and risk factors for Aspergillosis other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Other Diagnostic Studies
Skin Biopsy
- Skin biopsy is helpful in the diagnosis of cutaneous aspergillosis.
- Histopathologic examination with hematoxylin and eosin will variably demonstrate Aspergillus hyphae.[1]
- The Gomori methenamine silver stain, however, clearly detects hyphae, since the hyphal cell wall stains black, while the background tissue stains green.
- Aspergillus hyphae should have acute-angle branching and frequent septations on histopathological examination.
PCR
- A single negative PCR result is enough to exclude a diagnosis of a probable invasive aspergillosis.[2]
- While, two positive test results are required to confirm a diagnosis of aspergillosis.
Gallery
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This image depicts histopathologic changes indicating aspergillosis of the lung of a caged parrot caused by A. fumigatus. From Public Health Image Library (PHIL). [3]
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This image depicts histopathologic changes indicating aspergillosis of the lung of a caged parrot caused by A. fumigatus. From Public Health Image Library (PHIL). [3]
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Histopathology of aspergillosis of the lung of a caged sulfur-crested cockatoo caused by Aspergillus fumigatus. From Public Health Image Library (PHIL). [3]
References
- ↑ van Burik JA, Colven R, Spach DH (1998). "Cutaneous aspergillosis". J Clin Microbiol. 36 (11): 3115–21. PMC 105285. PMID 9774549.
- ↑ Mengoli C, Cruciani M, Barnes RA, Loeffler J, Donnelly JP (2009). "Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis". Lancet Infect Dis. 9 (2): 89–96. doi:10.1016/S1473-3099(09)70019-2. PMID 19179225.
- ↑ 3.0 3.1 3.2 "Public Health Image Library (PHIL)".
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