Aspergillosis other diagnostic studies: Difference between revisions
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===Skin Biopsy=== | ===Skin Biopsy=== | ||
* Skin biopsy is helpful in the diagnosis of cutaneous aspergillosis. | * Skin biopsy is helpful in the diagnosis of cutaneous aspergillosis. | ||
* Histopathologic examination with [[hematoxylin]] and [[eosin]] will variably demonstrate Aspergillus hyphae.<ref name="pmid9774549">{{cite journal| author=van Burik JA, Colven R, Spach DH| title=Cutaneous aspergillosis. | journal=J Clin Microbiol | year= 1998 | volume= 36 | issue= 11 | pages= 3115-21 | pmid=9774549 | doi= | pmc=PMC105285 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9774549 }} </ref> | * Histopathologic examination with [[hematoxylin]] and [[eosin]] will variably demonstrate ''Aspergillus'' hyphae.<ref name="pmid9774549">{{cite journal| author=van Burik JA, Colven R, Spach DH| title=Cutaneous aspergillosis. | journal=J Clin Microbiol | year= 1998 | volume= 36 | issue= 11 | pages= 3115-21 | pmid=9774549 | doi= | pmc=PMC105285 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9774549 }} </ref> | ||
* The Gomori methenamine [[silver stain]], however, clearly detects [[hyphae]], since the hyphal [[cell wall]] stains black, while the background tissue stains green. | * The Gomori methenamine [[silver stain]], however, clearly detects [[hyphae]], since the hyphal [[cell wall]] stains black, while the background tissue stains green. | ||
* Aspergillus [[hyphae]] should have acute-angle branching and frequent septations on histopathological examination. | * Aspergillus [[hyphae]] should have acute-angle branching and frequent septations on histopathological examination. |
Revision as of 23:59, 8 February 2016
Aspergillosis Microchapters |
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Aspergillosis other diagnostic studies On the Web |
American Roentgen Ray Society Images of Aspergillosis other diagnostic studies |
Risk calculators and risk factors for Aspergillosis other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Yazan Daaboul, M.D.; Serge Korjian M.D.
Overview
Skin biopsy may be helpful in the diagnosis of cutaneous aspergillosis.[1][2]
Other Diagnostic Studies
Skin Biopsy
- Skin biopsy is helpful in the diagnosis of cutaneous aspergillosis.
- Histopathologic examination with hematoxylin and eosin will variably demonstrate Aspergillus hyphae.[2]
- The Gomori methenamine silver stain, however, clearly detects hyphae, since the hyphal cell wall stains black, while the background tissue stains green.
- Aspergillus hyphae should have acute-angle branching and frequent septations on histopathological examination.
Gallery
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This image depicts histopathologic changes indicating aspergillosis of the lung of a caged parrot caused by A. fumigatus. From Public Health Image Library (PHIL). [3]
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This image depicts histopathologic changes indicating aspergillosis of the lung of a caged parrot caused by A. fumigatus. From Public Health Image Library (PHIL). [3]
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Histopathology of aspergillosis of the lung of a caged sulfur-crested cockatoo caused by Aspergillus fumigatus. From Public Health Image Library (PHIL). [3]
References
- ↑ Mengoli C, Cruciani M, Barnes RA, Loeffler J, Donnelly JP (2009). "Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis". Lancet Infect Dis. 9 (2): 89–96. doi:10.1016/S1473-3099(09)70019-2. PMID 19179225.
- ↑ 2.0 2.1 van Burik JA, Colven R, Spach DH (1998). "Cutaneous aspergillosis". J Clin Microbiol. 36 (11): 3115–21. PMC 105285. PMID 9774549.
- ↑ 3.0 3.1 3.2 "Public Health Image Library (PHIL)".