Bone or cartilage mass biopsy: Difference between revisions
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==Biopsy== | ==Biopsy== | ||
Common types of bone biopsy, include: | Common types of bone biopsy, include:<ref name="pmid16951637">{{cite journal |vauthors=Mankin HJ, Lange TA, Spanier SS |title=THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127 |journal=Clin. Orthop. Relat. Res. |volume=450 |issue= |pages=4–10 |year=2006 |pmid=16951637 |doi=10.1097/01.blo.0000229299.36969.b5 |url=}}</ref> | ||
*'''Open''' | *'''Open''' | ||
:*Gold standard for diagnosis of a bone tumor | :*Gold standard for diagnosis of a bone tumor | ||
:*Performed during surgery | :*Performed during surgery | ||
:*On malignant lesions, biopsy incisions are: longitudinal, small, and anatomically placed to minimize contamination of normal tissue | :*On malignant lesions, biopsy incisions are: longitudinal, small, and anatomically placed to minimize contamination of normal tissue | ||
:*Increased risk of complications | :*Increased risk of complications | ||
:*Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor | |||
*'''Closed''' | *'''Closed''' | ||
:*Less invasive and lower risk of tissue contamination with tumor cells | |||
:*Usually involves CT guidance | |||
:*Less risk of complications | |||
:*Less painful, and less costly | |||
:*Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 15:12, 11 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Bone biopsy findings associated with bone and cartilage tumors include
Biopsy
Common types of bone biopsy, include:[1]
- Open
- Gold standard for diagnosis of a bone tumor
- Performed during surgery
- On malignant lesions, biopsy incisions are: longitudinal, small, and anatomically placed to minimize contamination of normal tissue
- Increased risk of complications
- Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor
- Closed
- Less invasive and lower risk of tissue contamination with tumor cells
- Usually involves CT guidance
- Less risk of complications
- Less painful, and less costly
- Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade
References
- ↑ Mankin HJ, Lange TA, Spanier SS (2006). "THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127". Clin. Orthop. Relat. Res. 450: 4–10. doi:10.1097/01.blo.0000229299.36969.b5. PMID 16951637.