Bone or cartilage mass biopsy: Difference between revisions
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*'''Closed''' | *'''Closed''' | ||
:*Less invasive and lower risk of tissue contamination with tumor cells | :*Less invasive and lower risk of tissue contamination with tumor cells | ||
:*Usually involves CT | :*Usually involves CT image-guided percutaneous biopsy | ||
:*Less risk of complications | :*Less risk of complications | ||
:*Less painful, and less costly | :*Less painful, and less costly | ||
:*Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade | :*Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade | ||
*Common bone and cartilage tumors biopsy findings, include: | |||
:*Anastomosing bony trabeculae | |||
:*Calcifications surrounded by cells nests | |||
:*Increased/decreased osteoblasts and osteoclasts | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 15:58, 22 February 2016
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Bone or Cartilage Mass Microchapters |
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Diagnosis |
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Case Studies |
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Bone or cartilage mass biopsy On the Web |
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American Roentgen Ray Society Images of Bone or cartilage mass biopsy |
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Risk calculators and risk factors for Bone or cartilage mass biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Bone biopsy findings associated with bone and cartilage tumors will depend on tumor histology, common findings include: anastomosing bony trabeculae, calcifications surrounded by cells nests, and increased/decreased osteoblasts and osteoclasts.[1]
Biopsy
Common types of bone biopsy, include:[1]
- Open
- Gold standard for diagnosis of a bone tumor
- Performed during surgery
- On malignant lesions, biopsy incisions are: longitudinal, small, or anatomically placed to minimize contamination of normal tissue
- Increased risk of complications
- Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor
- Closed
- Less invasive and lower risk of tissue contamination with tumor cells
- Usually involves CT image-guided percutaneous biopsy
- Less risk of complications
- Less painful, and less costly
- Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade
- Common bone and cartilage tumors biopsy findings, include:
- Anastomosing bony trabeculae
- Calcifications surrounded by cells nests
- Increased/decreased osteoblasts and osteoclasts
References
- ↑ 1.0 1.1 Mankin HJ, Lange TA, Spanier SS (2006). "THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127". Clin. Orthop. Relat. Res. 450: 4–10. doi:10.1097/01.blo.0000229299.36969.b5. PMID 16951637.