Fibroma differential diagnosis: Difference between revisions

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Revision as of 20:04, 23 March 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Oral fibroma must be differentiated from squamous papilloma, giant cell fibroma, neurofibroma, peripheral giant cell granuloma, mucocele, and benign and malignant salivary gland tumors. Non-ossifying fibroma must be differentiated from fibrous cortical defect, aneurysmal bone cyst, chondromyxoid fibroma, fibrous dysplasia, desmoplastic fibroma, giant cell tumor of bone, and spindle cell lesions of bone. Ossifying fibroma must be differentiated from ossifying fibroma, fibrous dysplasia, adamantinoma, and osteoid osteoma. Chondromyxoid fibroma must be differentiated from aneurysmal bone cyst (ABC), giant cell tumor of bone (GCT), non ossifying fibroma, chondroblastoma, chondrosarcoma, and phosphaturic mesenchymal tumor. Desmoplastic fibroma must be differentiated from giant cell tumor of bone (GCT), non ossifying fibroma (NOF), fibrous dysplasia, low grade fibrosarcoma, unicameral bone cyst, chondromyxoid fibroma, periosteal desmoids, eosinophilic granuloma, low-grade intraosseous osteosarcoma, adamantinoma, and distant metastasis.^[1]^[1]^[1] ^[1]^[1]^[1]^[1]

Differential Diagnosis


Type of Fibroma	Differential Diagnosis

Ovarian fibroma	Large pedunculated subserosal uterine leiomyoma Thecoma Leiomyoma Fibrosarcoma Metastatic metaplastic carcinoma Endometriosis with extensive fibrosis.
Non-ossifying fibroma	Fibrous cortical defect Aneurysmal bone cyst Chondromyxoid fibroma Fibrous dysplasia Desmoplastic fibroma Giant cell tumor of bone Spindle cell lesions of bone
Ossifying Fibroma	Fibrous dysplasia Adamantinoma Osteoid osteoma
Chondromyxoid Fibroma	Aneurysmal bone cyst (ABC) Giant cell tumor of bone (GCT) Non ossifying fibroma Chondroblastoma Chondrosarcoma Phosphaturic mesenchymal tumor
Desmoplastic Fibroma	Giant cell tumor of bone (GCT) Non ossifying fibroma (NOF) Fibrous dysplasia Low grade fibrosarcoma Unicameral bone cyst Chondromyxoid fibroma Periosteal desmoids Eosinophilic granuloma Low-grade intraosseous osteosarcoma Adamantinoma Distant metastasis
Pleural Fibroma	Considerations for extremely well defined lesions include: Pleural lipoma Pleural fibrosarcoma Intercostal nerve neurilemoma (schwannoma) If not extremely well defined, broader considerations include: Organised inflammation Peripheral bronchogenic carcinoma Solitary pleural metastasis Also consider the differential for a single pleural mass which includes the following: Pleural tumors Solitary fibrous tumour of the pleura (pleural fibroma) Mesothelioma Localised mediastinal malignant mesothelioma Metastatic pleural disease, particularly from adenocarcinomas Pleural lymphoma Invasive thymoma Lipoma Pleural effusion Empyema Haemothorax Ewing sarcoma of chest wall, Askin tumor Intercostal nerve neurilemmoma Splenosis Tuberculosis
Renal Medullary Fibroma	Renal myxoma
Cemento-ossifying Fibroma	Fibrous dysplasia Ameloblastic fibro odontoma Odontoma Calcifying epithelial odontogenic tumour (Pindborg tumour) Odontogenic cyst Calcifying odontogenic cyst (Gorlin cyst) Osteochondroma Osteosarcoma Chondrosarcoma
Desmoplastic fibroblastoma (Collagenous fibroma)	Fibromatosis [[Elastofibroma] Low-grade fibromyxoid sarcoma.
Ameloblastic Fibroma	Ameloblastoma
Giant cell fibroma	Squamous Papilloma Irritation fibroma Pyogenic granuloma Peripheral giant cell granuloma.
Oral Fibroma	Squamous Papilloma Giant cell fibroma Neurofibroma Peripheral giant cell granuloma Mucocele Benign and malignant salivary gland tumors
Uterine Fibroma	Uterine leiomyosarcoma Uterine smooth muscle tumours of uncertain malignant potential Uterine lipoleiomyoma Ovarian masses Focal myometrial contraction (Braxton Hicks contraction): especially if seen during pregnancy Focal adenomyosis
Peripheral odontogenic fibroma	Inflammatory gingival hyperplasia Peripheral cemento-ossifying fibroma Peripheral giant cell granuloma
Peripheral odontogenic fibroma	Spindle cell lipoma Nuchal-type fibroma Fibromatosis colli

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Fibroma. Radiopedia(2015) http://radiopaedia.org/search?utf8=%E2%9C%93&q=fibroma&scope=all Accessed on March 12, 2016

Template:WH Template:WS

[radio-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Fibroma. Radiopedia(2015) http://radiopaedia.org/search?utf8=%E2%9C%93&q=fibroma&scope=all Accessed on March 12, 2016

[1]

@@ Line 3: / Line 3: @@
 {{CMG}}; {{AE}} {{Simrat}}
 ==Overview==
-Oral fibroma must be differentiated from squamous papilloma, giant cell fibroma, neurofibroma, peripheral giant cell granuloma, mucocele, and benign and malignant salivary gland tumors. Non-ossifying fibroma must be differentiated from fibrous cortical defect, aneurysmal bone cyst, chondromyxoid fibroma, fibrous dysplasia, desmoplastic fibroma,
+Oral fibroma must be differentiated from [[squamous papilloma]], [[giant cell fibroma]], [[neurofibroma]], [[peripheral giant cell]] granuloma, [[mucocele]], and benign and [[malignant salivary gland tumors]]. [[Non-ossifying fibroma]] must be differentiated from [[fibrous cortical defect]], [[aneurysmal bone cyst]], [[chondromyxoid fibroma]], [[fibrous dysplasia]], [[desmoplastic fibroma]], [[giant cell tumor]] of bone, and spindle cell lesions of bone. [[Ossifying fibroma]] must be differentiated from ossifying fibroma, [[fibrous dysplasia]], [[adamantinoma]], and [[osteoid osteoma]]. [[Chondromyxoid fibroma]] must be differentiated from [[aneurysmal bone cyst]] (ABC), [[giant cell tumor]] of bone (GCT), [[non ossifying fibroma]], [[chondroblastoma]], [[chondrosarcoma]], and phosphaturic mesenchymal tumor. [[Desmoplastic fibroma]] must be differentiated from [[giant cell tumor]] of bone (GCT), [[non ossifying fibroma]] (NOF), fibrous dysplasia, low grade fibrosarcoma, unicameral bone cyst, chondromyxoid fibroma, periosteal desmoids, eosinophilic granuloma, low-grade intraosseous osteosarcoma, [[adamantinoma]], and distant metastasis.<ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/search?utf8=%E2%9C%93&q=fibroma&scope=all Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/non-ossifying-fibroma-1 Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/ovarian-fibroma Accessed on March 12, 2016</ref> <ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/ossifying-fibroma Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/chondromyxoid-fibroma Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/cemento-ossifying-fibroma Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/uterine-leiomyoma Accessed on March 12, 2016</ref>
-giant cell tumour of bone, and spindle cell lesions of bone. Ossifying fibroma must be differentiated from ossifying fibroma, fibrous dysplasia, adamantinoma, and osteoid osteoma. Chondromyxoid fibroma must be differentiated from aneurysmal bone cyst (ABC), giant cell tumour of bone (GCT), non ossifying fibroma, chondroblastoma, chondrosarcoma, and phosphaturic mesenchymal tumor. Desmoplastic fibroma must be differentiated from giant cell tumour of bone (GCT), non ossifying fibroma (NOF), fibrous dysplasia, low grade fibrosarcoma, unicameral bone cyst, chondromyxoid fibroma, periosteal desmoids, eosinophilic granuloma, low-grade intraosseous osteosarcoma, adamantinoma, and distant metastasis.<ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/search?utf8=%E2%9C%93&q=fibroma&scope=all Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/non-ossifying-fibroma-1 Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/ovarian-fibroma Accessed on March 12, 2016</ref> <ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/ossifying-fibroma Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/chondromyxoid-fibroma Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/cemento-ossifying-fibroma Accessed on March 12, 2016</ref><ref name="radio"> Fibroma. Radiopedia(2015) http://radiopaedia.org/articles/uterine-leiomyoma Accessed on March 12, 2016</ref>
 ==Differential Diagnosis==
@@ Line 17: / Line 16: @@
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Large pedunculated subserosal uterine leiomyoma
-*Thecoma
+*[[Thecoma]]
-*Leiomyoma
+*[[Leiomyoma]]
-*Fibrosarcoma
+*[[Fibrosarcoma]]
 *Metastatic metaplastic carcinoma
 *Endometriosis with extensive fibrosis.
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Non-ossifying fibroma
+:[[Non-ossifying fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Fibrous cortical defect
+*[[Fibrous cortical defect]]
-*Aneurysmal bone cyst
+*[[Aneurysmal bone cyst]]
-*Chondromyxoid fibroma
+*[[Chondromyxoid fibroma]]
 *Fibrous dysplasia
-*Desmoplastic fibroma
+*[[Desmoplastic fibroma]]
-*Giant cell tumour of bone
+*[[Giant cell tumor]] of bone
 *Spindle cell lesions of bone
 |-
@@ Line 37: / Line 36: @@
 :Ossifying Fibroma
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Fibrous dysplasia
+*[[Fibrous dysplasia]]
-*Adamantinoma
+*[[Adamantinoma]]
-*Osteoid osteoma
+*[[Osteoid osteoma]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Chondromyxoid Fibroma
+:[[Chondromyxoid Fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Aneurysmal bone cyst (ABC)
+*[[Aneurysmal bone cyst]] (ABC)
-*Giant cell tumour of bone (GCT)
+*[[Giant cell tumor]] of bone (GCT)
-*Non ossifying fibroma
+*[[Non ossifying fibroma]]
-*Chondroblastoma
+*[[Chondroblastoma]]
-*Chondrosarcoma
+*[[Chondrosarcoma]]
 *Phosphaturic mesenchymal tumor
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Desmoplastic Fibroma
+:[[Desmoplastic Fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Giant cell tumour of bone (GCT)
+*[[Giant cell tumor]] of bone (GCT)
-*Non ossifying fibroma (NOF)
+*[[Non ossifying fibroma]] (NOF)
-*Fibrous dysplasia
+*[[Fibrous dysplasia]]
-*Low grade fibrosarcoma
+*Low grade [[fibrosarcoma]]
 *Unicameral bone cyst
-*Chondromyxoid fibroma
+*[[Chondromyxoid fibroma]]
 *Periosteal desmoids
 *Eosinophilic granuloma
 *Low-grade intraosseous osteosarcoma
-*Adamantinoma
+*[[Adamantinoma]]
 *Distant metastasis
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Pleural Fibroma
+:[[Pleural Fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 Considerations for extremely well defined lesions include:
-*Pleural lipoma
+*[[Pleural lipoma]]
-*Pleural fibrosarcoma
+*Pleural [[fibrosarcoma]]
-*Intercostal nerve neurilemoma (schwannoma)
+*[[Intercostal nerve neurilemoma]] (schwannoma)
 If not extremely well defined, broader considerations include:
 *Organised inflammation
@@ Line 78: / Line 77: @@
 *Solitary pleural metastasis
 Also consider the differential for a single pleural mass which includes the following:
-*Pleural tumours
+*Pleural tumors
 **Solitary fibrous tumour of the pleura (pleural fibroma)
 **Mesothelioma
 **Localised mediastinal malignant mesothelioma
-*Metastatic pleural disease, particularly from adenocarcinomas
+*Metastatic pleural disease, particularly from [[adenocarcinomas]]
 *Pleural lymphoma
 *Invasive thymoma
 *Lipoma
-*Pleural effusion
+*[[Pleural effusion]]
-*Empyema
+*[[Empyema]]
-*Haemothorax
+*[[Haemothorax]]
-*Ewing sarcoma of chest wall, Askin tumour
+*[[Ewing sarcoma]] of chest wall, Askin tumor
 *Intercostal nerve neurilemmoma
 *Splenosis
-*Tuberculosis
+*[[Tuberculosis]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Renal Medullary Fibroma
+:[[Renal Medullary Fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Renal myxoma
+*[[Renal myxoma]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
 :Cemento-ossifying Fibroma
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Fibrous dysplasia
+*[[Fibrous dysplasia]]
 *Ameloblastic fibro odontoma
-*Odontoma
+*[[Odontoma]]
 *Calcifying epithelial odontogenic tumour (Pindborg tumour)
 *Odontogenic cyst
 *Calcifying odontogenic cyst (Gorlin cyst)
-*Osteochondroma
+*[[Osteochondroma]]
-*Osteosarcoma
+*[[Osteosarcoma]]
-*Chondrosarcoma
+*[[Chondrosarcoma]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Desmoplastic fibroblastoma (Collagenous fibroma)
+:[[Desmoplastic fibroblastoma]] (Collagenous fibroma)
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Fibromatosis
+*[[Fibromatosis]]
-*Elastofibroma
+*[[Elastofibroma]
 *Low-grade fibromyxoid sarcoma.
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Ameloblastic Fibroma
+:[[Ameloblastic Fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Ameloblastoma
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Giant cell fibroma
+:[[Giant cell fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Squamous Papilloma
+*[[Squamous Papilloma]]
 *Irritation fibroma
 *Pyogenic granuloma
@@ Line 143: / Line 142: @@
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Uterine Fibroma
+:[[Uterine Fibroma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Uterine leiomyosarcoma
+*[[Uterine leiomyosarcoma]]
 *Uterine smooth muscle tumours of uncertain malignant potential
 *Uterine lipoleiomyoma
 *Ovarian masses
 *Focal myometrial contraction (Braxton Hicks contraction): especially if seen during pregnancy
-*Focal adenomyosis
+*Focal [[adenomyosis]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
@@ Line 156: / Line 155: @@
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Inflammatory gingival hyperplasia
-*Peripheral cemento-ossifying fibroma
+*Peripheral [[cemento-ossifying fibroma]]
-*Peripheral giant cell granuloma.
+*Peripheral [[giant cell granuloma]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |

Fibroma differential diagnosis: Difference between revisions

Revision as of 20:04, 23 March 2016

Overview

Differential Diagnosis

References

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