Fibroma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2],Simrat Sarai, M.D. [3]

Overview

There is no classification system established for fibroma. Based on the pathophysiology and location of the tumor, fibroma may be classified into hard fibroma, soft fibroma, angiofibroma, cystic fibroma, chondromyxoid fibroma, desmoplastic fibroma, nonossifying fibroma, ossifying fibroma, nuchal fibroma, collagenous fibroma, fibroma of tendon sheath, perifollicular fibroma, pleomorphic fibroma, uterine fibroma, neurofibroma, and ovarian fibroma.^[1]

Classification

Based on the pathophysiology and location of the tumor fibroma may be classified into the following types, which is shown below in a tabular form:^[2]^[3]^[4] ^[5]^[6]^[7]^[8] ^[9]^[10]^[11] ^[12]^[13] ^[14]


Type of Fibroma	Features

Hard Fibroma	The hard fibroma (fibroma durum) consists of many fibers and a few cells, e.g. in the skin it is called dermatofibroma (fibroma simplex or nodulus cutaneous). A special form is the keloid, which derives from hyperplastic growth of scars.
Soft Fibroma	The soft fibroma (fibroma molle) or fibroma with a shaft (acrochordon, skin tag, fibroma pendulans) consist of many loosely connected cells and less fibrous tissue. They mostly appear on the neck, armpits or groin.
Other types of fibroma	The fibroma cavernosum or angiofibroma It consists of many dilated vessels, it is a vasoactive tumor occurring almost exclusively in adolescent males. The cystic fibroma (fibroma cysticum) It has central softening or dilated lymphatic vessels. Myxofibroma The myxofibroma (fibroma myxomatodes) is produced by liquefaction of the underlying soft tissue. Cemento-ossifying fibroma The cemento-ossifying fibroma is hard and fibrous, most frequently seen on the jaw or in the mouth, sometimes in connection with a fracture or another type of injury. Other fibromas: Chondromyxoid fibroma Desmoplastic fibroma Nonossifying fibroma Ossifying fibroma Nuchal fibroma Collagenous fibroma Fibroma of tendon sheath Perifollicular fibroma Pleomorphic fibroma Uterine fibroma Neurofibroma
Ovarian Fibroma	It appears in the sex cord-stromal tumor group of ovarian neoplasms. Upon gross pathological inspection, ovary fibromas are firm and white or tan. Variants with edema are especially likely to be associated with Meigs' syndrome. On microscopic examination, there are intersecting bundles of spindle cells producing collagen. There may be thecomatous areas (fibrothecoma). The presence of an ovarian fibroma can cause ovarian torsion in some cases.

References

↑ fibroma. Wikipedia(2015) https://en.wikipedia.org/wiki/Fibroma Accessed on February 25, 2016
↑ Boujoual M, Hakimi I, Kouach J, Oukabli M, Moussaoui DR, Dehayni M (2015). "Large twisted ovarian fibroma in menopausal women: a case report". Pan Afr Med J. 20: 322. doi:10.11604/pamj.2015.20.322.5998. PMC 4491469. PMID 26175813.
↑ Chen H, Liu Y, Shen LF, Jiang MJ, Yang ZF, Fang GP (November 2016). "Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison". J Ovarian Res. 9 (1): 81. doi:10.1186/s13048-016-0291-2. PMC 5120502. PMID 27876070.
↑ Matsuda K, Tateishi S, Akazawa Y, Kinoshita A, Yoshida S, Morisaki S, Fukushima A, Matsuwaki T, Yoshiura KI, Nakashima M (October 2016). "Rapid growth of mitotically active cellular fibroma of the ovary: a case report and review of the literature". Diagn Pathol. 11 (1): 101. doi:10.1186/s13000-016-0554-7. PMID 27770806.
↑ Takenaga RK, Frassica FJ, McCarthy EF (2007). "Subperiosteal chondromyxoid fibroma: a report of two cases". Iowa Orthop J. 27: 104–7. PMC 2150655. PMID 17907440.
↑ Sharma H, Jane MJ, Reid R (June 2006). "Chondromyxoid fibroma of the foot and ankle: 40 years' Scottish bone tumour registry experience". Int Orthop. 30 (3): 205–9. doi:10.1007/s00264-005-0046-y. PMC 2532097. PMID 16547720.
↑ Manta L, Suciu N, Toader O, Purcărea RM, Constantin A, Popa F (2016). "The etiopathogenesis of uterine fibromatosis". J Med Life. 9 (1): 39–45. PMC 5152611. PMID 27974911.
↑ Borahay MA, Al-Hendy A, Kilic GS, Boehning D (April 2015). "Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy". Mol. Med. 21: 242–56. doi:10.2119/molmed.2014.00053. PMC 4503645. PMID 25879625.
↑ Wang TT, Zhang R, Wang L, Chen Y, Dong Q, Li TJ (March 2014). "Two cases of multiple ossifying fibromas in the jaws". Diagn Pathol. 9: 75. doi:10.1186/1746-1596-9-75. PMC 3974450. PMID 24678936.
↑ Chen Y, Hu DY, Wang TT, Zhang R, Dong Q, Xu ZX, Wang L, Li TJ (September 2016). "CDC73 gene mutations in sporadic ossifying fibroma of the jaws". Diagn Pathol. 11 (1): 91. doi:10.1186/s13000-016-0532-0. PMC 5034632. PMID 27658992.
↑ Bowers LM, Cohen DM, Bhattacharyya I, Pettigrew JC, Stavropoulos MF (June 2013). "The non-ossifying fibroma: a case report and review of the literature". Head Neck Pathol. 7 (2): 203–10. doi:10.1007/s12105-012-0399-7. PMID 23008139.
↑ Schneider M, Zimmermann AC, Depprich RA, Kübler NR, Engers R, Naujoks CD, Handschel J (November 2009). "Desmoplastic fibroma of the mandible--review of the literature and presentation of a rare case". Head Face Med. 5: 25. doi:10.1186/1746-160X-5-25. PMID 19930688.
↑ Aremu AA, Oyedeji OA, Asaleye CM, Adetiloye VA (2013). "An elusive chest coin in an African child: a pleural fibroma's long, tortuous path to freedom". Pan Afr Med J. 14: 16. doi:10.11604/pamj.2013.14.16.1874. PMC 3597858. PMID 23503999.
↑ Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, Ozawa T, Nakayama H, Shinozaki M, Sasai D, Ishiwatari T, Takuma K, Shibuya K (March 2012). "Literature survey on epidemiology and pathology of cardiac fibroma". Eur. J. Med. Res. 17: 5. doi:10.1186/2047-783X-17-5. PMC 3351722. PMID 22472419.

Template:WH Template:WS

[wiki-1] roma. Wikipedia(2015) https://en.wikipedia.org/wiki/Fibroma Accessed on February 25, 2016

[pmid26175813-2] Boujoual M, Hakimi I, Kouach J, Oukabli M, Moussaoui DR, Dehayni M (2015). "Large twisted ovarian fibroma in menopausal women: a case report". Pan Afr Med J. 20: 322. doi:10.11604/pamj.2015.20.322.5998. PMC 4491469. PMID 26175813.

[pmid27876070-3] Chen H, Liu Y, Shen LF, Jiang MJ, Yang ZF, Fang GP (November 2016). "Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison". J Ovarian Res. 9 (1): 81. doi:10.1186/s13048-016-0291-2. PMC 5120502. PMID 27876070.

[pmid27770806-4] Matsuda K, Tateishi S, Akazawa Y, Kinoshita A, Yoshida S, Morisaki S, Fukushima A, Matsuwaki T, Yoshiura KI, Nakashima M (October 2016). "Rapid growth of mitotically active cellular fibroma of the ovary: a case report and review of the literature". Diagn Pathol. 11 (1): 101. doi:10.1186/s13000-016-0554-7. PMID 27770806.

[pmid17907440-5] Takenaga RK, Frassica FJ, McCarthy EF (2007). "Subperiosteal chondromyxoid fibroma: a report of two cases". Iowa Orthop J. 27: 104–7. PMC 2150655. PMID 17907440.

[pmid16547720-6] Sharma H, Jane MJ, Reid R (June 2006). "Chondromyxoid fibroma of the foot and ankle: 40 years' Scottish bone tumour registry experience". Int Orthop. 30 (3): 205–9. doi:10.1007/s00264-005-0046-y. PMC 2532097. PMID 16547720.

[pmid27974911-7] Manta L, Suciu N, Toader O, Purcărea RM, Constantin A, Popa F (2016). "The etiopathogenesis of uterine fibromatosis". J Med Life. 9 (1): 39–45. PMC 5152611. PMID 27974911.

[pmid25879625-8] Borahay MA, Al-Hendy A, Kilic GS, Boehning D (April 2015). "Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy". Mol. Med. 21: 242–56. doi:10.2119/molmed.2014.00053. PMC 4503645. PMID 25879625.

[pmid24678936-9] Wang TT, Zhang R, Wang L, Chen Y, Dong Q, Li TJ (March 2014). "Two cases of multiple ossifying fibromas in the jaws". Diagn Pathol. 9: 75. doi:10.1186/1746-1596-9-75. PMC 3974450. PMID 24678936.

[pmid27658992-10] Chen Y, Hu DY, Wang TT, Zhang R, Dong Q, Xu ZX, Wang L, Li TJ (September 2016). "CDC73 gene mutations in sporadic ossifying fibroma of the jaws". Diagn Pathol. 11 (1): 91. doi:10.1186/s13000-016-0532-0. PMC 5034632. PMID 27658992.

[pmid23008139-11] Bowers LM, Cohen DM, Bhattacharyya I, Pettigrew JC, Stavropoulos MF (June 2013). "The non-ossifying fibroma: a case report and review of the literature". Head Neck Pathol. 7 (2): 203–10. doi:10.1007/s12105-012-0399-7. PMID 23008139.

[pmid19930688-12] Schneider M, Zimmermann AC, Depprich RA, Kübler NR, Engers R, Naujoks CD, Handschel J (November 2009). "Desmoplastic fibroma of the mandible--review of the literature and presentation of a rare case". Head Face Med. 5: 25. doi:10.1186/1746-160X-5-25. PMID 19930688.

[pmid23503999-13] Aremu AA, Oyedeji OA, Asaleye CM, Adetiloye VA (2013). "An elusive chest coin in an African child: a pleural fibroma's long, tortuous path to freedom". Pan Afr Med J. 14: 16. doi:10.11604/pamj.2013.14.16.1874. PMC 3597858. PMID 23503999.

[pmid22472419-14] Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, Ozawa T, Nakayama H, Shinozaki M, Sasai D, Ishiwatari T, Takuma K, Shibuya K (March 2012). "Literature survey on epidemiology and pathology of cardiac fibroma". Eur. J. Med. Res. 17: 5. doi:10.1186/2047-783X-17-5. PMC 3351722. PMID 22472419.

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Fibroma classification

Overview

Classification

References

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