Beriberi overview: Difference between revisions
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{{Beriberi}} | {{Beriberi}} | ||
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==Overview== | ==Overview== | ||
Beriberi is a dietary-deficiency disease caused by a lack of [[thiamine]] in the diet. Thiamine, initially named "the anti-beriberi factor" in 1926 was the first B vitamin to be identified and is therefore referred to as vitamin B1. Thiamine is soluble in water and partly soluble in [[alcohol]]. It consists of a pyrimidine and a thiazole moiety, both of which are essential for its activity. Thiamine functions in the decarboxylation of α-ketoacids, such as pyruvate α-ketoglutarate, and branched-chain amino acids and thus is a source of energy generation. In addition, thiamine pyrophosphate acts as a coenzyme for a transketolase reaction that mediates the conversion of hexose and pentose phosphates. | Beriberi is a dietary-deficiency disease caused by a lack of [[thiamine]] in the diet. Thiamine, initially named "the anti-beriberi factor" in 1926 was the first B vitamin to be identified and is therefore referred to as vitamin B1. Thiamine is soluble in water and partly soluble in [[alcohol]]. It consists of a pyrimidine and a thiazole moiety, both of which are essential for its activity. Thiamine functions in the decarboxylation of α-ketoacids, such as pyruvate α-ketoglutarate, and branched-chain amino acids and thus is a source of energy generation. In addition, thiamine pyrophosphate acts as a coenzyme for a transketolase reaction that mediates the conversion of hexose and pentose phosphates. | ||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating {{PAGENAME}} from Other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
===Complications=== | |||
===Prognosis=== | |||
==Diagnosis== | |||
===Diagnostic Criteria=== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Prevention=== | |||
==References== | ==References== | ||
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{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[Category:Endocrinology]] | |||
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[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] |
Revision as of 16:03, 22 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Beriberi is a dietary-deficiency disease caused by a lack of thiamine in the diet. Thiamine, initially named "the anti-beriberi factor" in 1926 was the first B vitamin to be identified and is therefore referred to as vitamin B1. Thiamine is soluble in water and partly soluble in alcohol. It consists of a pyrimidine and a thiazole moiety, both of which are essential for its activity. Thiamine functions in the decarboxylation of α-ketoacids, such as pyruvate α-ketoglutarate, and branched-chain amino acids and thus is a source of energy generation. In addition, thiamine pyrophosphate acts as a coenzyme for a transketolase reaction that mediates the conversion of hexose and pentose phosphates.