Necrotizing fasciitis epidemiology and demographics: Difference between revisions
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===Mortality Rate=== | ===Mortality Rate=== | ||
*Early intervention remains the only method of reducing mortality and morbidity in necrotizing fasciitis patients. | |||
*The mortality rate in necrotizing fasciitis is 24%-34%.<ref name="pmid4977757">{{cite journal| author=Ryter A, Hirota Y, Jacob F| title=DNA-membrane complex and nuclear segregation in bacteria. | journal=Cold Spring Harb Symp Quant Biol | year= 1968 | volume= 33 | issue= | pages= 669-76 | pmid=4977757 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4977757 }} </ref> | *The mortality rate in necrotizing fasciitis is 24%-34%.<ref name="pmid4977757">{{cite journal| author=Ryter A, Hirota Y, Jacob F| title=DNA-membrane complex and nuclear segregation in bacteria. | journal=Cold Spring Harb Symp Quant Biol | year= 1968 | volume= 33 | issue= | pages= 669-76 | pmid=4977757 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4977757 }} </ref> | ||
*It mainly depends on the time of medical and surgical interventions and extent of spread of infection. | *It mainly depends on the time of medical and surgical interventions and extent of spread of infection. | ||
Revision as of 22:47, 11 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Epidemiology and Demographics
Prevalence
Incidence
- Since 2010, approximately 700 to 1100 cases of necrotizing fasciitis caused by group A streptococcus occur each year in the United states.[1]
- The incidence of necrotizing fasciitis in adults is 0.40 cases per 100,000 people/year and the incidence in children is higher at 0.08 cases per 100,000 people/year.[2][3]
Mortality Rate
- Early intervention remains the only method of reducing mortality and morbidity in necrotizing fasciitis patients.
- The mortality rate in necrotizing fasciitis is 24%-34%.[4]
- It mainly depends on the time of medical and surgical interventions and extent of spread of infection.
- The mortality rate of necrotizing fasciitis increases from 9% to 63% if associated with mysositis and streptococcal toxic shock syndrome.
| Types | Mortality |
|---|---|
| Type 1 | Variable, depends on underlying comorbidities |
| Type 2 | >32% depends on associated myositis or toxic shock |
| Type 3 | 30- 40% |
| Type 4 | >47% (higher if immunocompromised) |
Age
Necrotizing fasciitis occurs in all age groups but slightly more common among >50 years age.[5]
Gender
Race
Developed countries
Developing countries
References
- ↑ Centers for Disease Control and Prevention (2016)http://www.cdc.gov/features/necrotizingfasciitis/ Accessed on september 6, 2016
- ↑ File TM, Tan JS, DiPersio JR (1998). "Group A streptococcal necrotizing fasciitis. Diagnosing and treating the "flesh-eating bacteria syndrome"". Cleve Clin J Med. 65 (5): 241–9. PMID 9599907.
- ↑ Chaouat Y, Chaouat D (1988). "[Primary hyperparathyroidism. History]". Rev Rhum Mal Osteoartic. 55 (7): 475–8. PMID 3051309.
- ↑ Ryter A, Hirota Y, Jacob F (1968). "DNA-membrane complex and nuclear segregation in bacteria". Cold Spring Harb Symp Quant Biol. 33: 669–76. PMID 4977757.
- ↑ Machado, Norman Oneil. "Necrotizing fasciitis: The importance of early diagnosis, prompt surgical debridement and adjuvant therapy." North Am J Med Sci 3 (2011): 107-118.