Membranoproliferative glomerulonephritis: Difference between revisions
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== [[Membranoproliferative glomerulonephritis overview|Overview]] == | == [[Membranoproliferative glomerulonephritis overview|Overview]] == | ||
Membranoproliferative Glomerulonephritis (MPGN) is a relatively uncommon inflammatory glomerulopathy that can cause chronic nephritis. Based on the histological pattern of glomerular injury it has been described as a chronic kidney disease found mostly in children and young adults. Like many forms of glomerulopathies, membranoproliferative glomerulonephritis (glomerulopathy) has been a diagnosis of tissue pathology rather the diagnosis of a specific disease entity. Therefore the term membranoploriferative glomerulonephritis (MPGN) relates to a pattern of glomerular injury characterized by mesangial proliferation and expansion, lobularization of the glomerular tufts and double contourswhich can be caused by many disease states | |||
Glomerular injury occurs due to deposition of immune complexes on the glomerular mesangium or on the glomerular basement membrane. MPGN has been categorized into 3 types based on the histological pattern of glomerular damage. Clinically, MPGN often present with hematuria, varying degrees of proteinuria, with or without Glomerular filtration rate impairment depending on the severity of glomerular injury, and the underlying etiology. | |||
== [[Membranoproliferative glomerulonephritis historical perspective|Historical Perspective]] == | == [[Membranoproliferative glomerulonephritis historical perspective|Historical Perspective]] == | ||
Revision as of 19:43, 17 November 2016
| Membranoproliferative glomerulonephritis | |
| ICD-10 | N00-N08 with .2 suffix |
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| ICD-9 | 581.2, 582.2, 583.2 |
| MeSH | D015432 |
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Membranoproliferative glomerulonephritis Microchapters |
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Differentiating Membranoproliferative glomerulonephritis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Membranoproliferative glomerulonephritis On the Web |
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American Roentgen Ray Society Images of Membranoproliferative glomerulonephritis |
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Directions to Hospitals Treating Membranoproliferative glomerulonephritis |
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Risk calculators and risk factors for Membranoproliferative glomerulonephritis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ali Poyan Mehr, M.D. [2]; Associate Editor-In-Chief: Olufunmilola Olubukola M.D.[3]Cafer Zorkun, M.D., Ph.D. [4]
Overview
Membranoproliferative Glomerulonephritis (MPGN) is a relatively uncommon inflammatory glomerulopathy that can cause chronic nephritis. Based on the histological pattern of glomerular injury it has been described as a chronic kidney disease found mostly in children and young adults. Like many forms of glomerulopathies, membranoproliferative glomerulonephritis (glomerulopathy) has been a diagnosis of tissue pathology rather the diagnosis of a specific disease entity. Therefore the term membranoploriferative glomerulonephritis (MPGN) relates to a pattern of glomerular injury characterized by mesangial proliferation and expansion, lobularization of the glomerular tufts and double contourswhich can be caused by many disease states Glomerular injury occurs due to deposition of immune complexes on the glomerular mesangium or on the glomerular basement membrane. MPGN has been categorized into 3 types based on the histological pattern of glomerular damage. Clinically, MPGN often present with hematuria, varying degrees of proteinuria, with or without Glomerular filtration rate impairment depending on the severity of glomerular injury, and the underlying etiology.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Membranoproliferative glomerulonephritis from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies