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==CDC Case Definitions==
in 2009, the [[CDC]] published the following case definition for case classification of congenital rubella syndrome:  
===Suspected Case===
An infant who does not meet the criteria for a probable or confirmed case but who has one or more of the following findings:
*[[Cataract]]s
*Congenital [[glaucoma]]
*[[Congenital heart disease]] (most commonly [[patent ductus arteriosus]] or peripheral [[pulmonary artery stenosis]])
*[[Hearing impairment]]
*Pigmentary [[retinopathy]]
*[[Purpura]]
*[[Hepatosplenomegaly]]
*[[Jaundice]]
*[[Microcephaly]]
*[[Developmental delay]]
*[[Meningoencephalitis]]
*Radiolucent bone disease


===Probable Case===
An infant who does not have laboratory confirmation of rubella infection but has at least two of the following, without a more plausible etiology:
*[[Cataract]]s or congenital [[glaucoma]],
*[[Congenital heart disease]] (most commonly patent ductus arteriosus or peripheral pulmonary artery stenosis),
*[[Hearing impairment]]
*Pigmentary [[retinopathy]]
OR
An infant who does not have laboratory confirmation of rubella infection but has at least one or more of the following, without a more plausible etiology:
*[[Cataract]]s or congenital [[glaucoma]],
*[[Congenital heart disease]] (most commonly [[patent ductus arteriosus]] or peripheral [[pulmonary artery stenosis]]),
*[[Hearing impairment]]
*Pigmentary [[retinopathy]]
AND one or more of the following:
*[[Purpura]]
*[[Hepatosplenomegaly]]
*[[Microcephaly]]
*[[Developmental delay]]
*[[Meningoencephalitis]]
*Radiolucent bone disease
===Confirmed Case===
An infant with at least one of the symptoms clinically consistent with congenital rubella syndrome listed above; and laboratory evidence of congenital rubella infection demonstrated by:
*Isolation of [[rubella virus]] or detection of rubella-specific immunoglogulin M ([[IgM]]) antibody, or infant rubella antibody level that persists at a higher level and for a longer period of time than expected from passive transfer of maternal antibody (i.e., rubella titer that does not drop at the expected rate of a two-fold decline per month), or a specimen that is PCR-positive for [[rubella virus]].


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Disease]]
[[Category:Pediatrics]]
[[Category:Neonatology]]
[[Category:Congenital disorders]]
[[Category:Infectious disease]]
[[Category:Syndromes]]
[[Category:Needs overview]]
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Revision as of 16:06, 5 January 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2], Dima Nimri, M.D. [3]

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in 2009, the CDC published the following case definition for case classification of congenital rubella syndrome:


References

Template:WH Template:WS

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