Congenital rubella syndrome laboratory findings: Difference between revisions
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=== Post-natal Serologic Testing === | === Post-natal Serologic Testing === | ||
====== Isolation of Virus ====== | |||
====== Serological Testing ====== | |||
Several serological investigations can be done to confirm CRS. These include detection of IgM or IgG antibodies or IgG avidity. | |||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 22:34, 16 January 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
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Congenital Rubella Syndrome Microchapters |
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Differentiating Congenital Rubella Syndrome from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Congenital rubella syndrome laboratory findings On the Web |
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American Roentgen Ray Society Images of Congenital rubella syndrome laboratory findings |
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Directions to Hospitals Treating Congenital rubella syndrome |
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Risk calculators and risk factors for Congenital rubella syndrome laboratory findings |
Overview
Laboratory Findings
Prenatal Testing
Invasive Techniques
Several invasive techniques can be done during pregnancy, depending on the gestational age. These techniques include:[1][2][3][4][5]
| Technique | Timing/ Gestational age at which it is performed | Results | Complications |
|---|---|---|---|
| Amniocentesis | after 15 weeks |
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| Fetal blood sampling | after 18-20 weeks | ||
| Chorionic villus sampling | after 11 weeks |
Post-natal Serologic Testing
Isolation of Virus
Serological Testing
Several serological investigations can be done to confirm CRS. These include detection of IgM or IgG antibodies or IgG avidity.
References
- ↑ De Santis M, Cavaliere AF, Straface G, Caruso A (2006). "Rubella infection in pregnancy". Reprod. Toxicol. 21 (4): 390–8. doi:10.1016/j.reprotox.2005.01.014. PMID 16580940.
- ↑ Morgan-Capner P, Hodgson J, Hambling MH, Dulake C, Coleman TJ, Boswell PA, Watkins RP, Booth J, Stern H, Best JM (1985). "Detection of rubella-specific IgM in subclinical rubella reinfection in pregnancy". Lancet. 1 (8423): 244–6. PMID 2857319.
- ↑ Ho-Terry L, Terry GM, Londesborough P, Rees KR, Wielaard F, Denissen A (1988). "Diagnosis of fetal rubella infection by nucleic acid hybridization". J. Med. Virol. 24 (2): 175–82. PMID 3351485.
- ↑ Terry GM, Ho-Terry L, Warren RC, Rodeck CH, Cohen A, Rees KR (1986). "First trimester prenatal diagnosis of congenital rubella: a laboratory investigation". Br Med J (Clin Res Ed). 292 (6525): 930–3. PMC 1339854. PMID 3083942.
- ↑ Valente P, Sever JL (1994). "In utero diagnosis of congenital infections by direct fetal sampling". Isr. J. Med. Sci. 30 (5–6): 414–20. PMID 8034496.