Amoebic liver abscess laboratory findings: Difference between revisions
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:*Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of ''[[Entamoeba|E dispar]]'' | :*Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of ''[[Entamoeba|E dispar]]'' | ||
:*If positive it suggests the diagnosis of amoebiasis. | :*If positive it suggests the diagnosis of amoebiasis. | ||
:*Cysts must be differentiated from ''[[Entamoeba|Entamoeba hartmanni]]'', ''[[Endolimax nana]]'', and ''[[Entamoeba|Entamoeba coli]]''. | |||
*Examination for trophozoites | *Examination for trophozoites | ||
:*As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken. | :*As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken. | ||
:*A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used. | :*A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used. | ||
:*Trophozoites must be differentiated with neutrophils. | |||
*Findings suggestive of amoebic colitis include: | *Findings suggestive of amoebic colitis include: | ||
:*Charcot-leyden crystal protein | :*Charcot-leyden crystal protein | ||
:*Positive test for heme | :*Positive test for heme | ||
:*A paucity of neutrophils | :*A paucity of neutrophils | ||
'''Stool antigen detection''' | |||
Revision as of 16:14, 8 February 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Laboratory Findings
Laboratory tests consistent with diagnosis of Amoebic liver abscess include:
Complete blood picture
- Heamoglobin <10g/dl
- Leukocytosis
- Neutrophilia
ESR and CRP
Elevated ESR and C-reactive protein[1]
Liver function tests
- Acte infection
- Elevated aspartate aminotransferase
- Normal alkaline phosphatase
- Chronic infection
- Elevated aspartate aminotransferase
- Elevated alkaline phosphatase
Stool Examination
- Microscopic stool examination for cysts
- Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of E dispar
- If positive it suggests the diagnosis of amoebiasis.
- Cysts must be differentiated from Entamoeba hartmanni, Endolimax nana, and Entamoeba coli.
- Examination for trophozoites
- As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken.
- A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used.
- Trophozoites must be differentiated with neutrophils.
- Findings suggestive of amoebic colitis include:
- Charcot-leyden crystal protein
- Positive test for heme
- A paucity of neutrophils
Stool antigen detection
Blood test for amoebiasis and stool testing for amoebiasis
References
- ↑ Blessmann J, Binh HD, Hung DM, Tannich E, Burchard G (2003). "Treatment of amoebic liver abscess with metronidazole alone or in combination with ultrasound-guided needle aspiration: a comparative, prospective and randomized study". Trop Med Int Health. 8 (11): 1030–4. PMID 14629771.