Amoebic liver abscess laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory tests consistent with diagnosis of Amoebic liver abscess include: | Laboratory tests consistent with diagnosis of Amoebic liver abscess include:<ref name="pmid14557296">{{cite journal| author=Tanyuksel M, Petri WA| title=Laboratory diagnosis of amebiasis. | journal=Clin Microbiol Rev | year= 2003 | volume= 16 | issue= 4 | pages= 713-29 | pmid=14557296 | doi= | pmc=207118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14557296 }} </ref> | ||
'''Complete blood picture''' | '''Complete blood picture''' | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Laboratory Findings
Laboratory tests consistent with diagnosis of Amoebic liver abscess include:[1]
Complete blood picture
- Heamoglobin <10g/dl
- Leukocytosis
- Neutrophilia
ESR and CRP
Elevated ESR and C-reactive protein[2]
Liver function tests
- Acte infection
- Elevated aspartate aminotransferase
- Normal alkaline phosphatase
- Chronic infection
- Elevated aspartate aminotransferase
- Elevated alkaline phosphatase
Stool Examination
- Microscopic stool examination for cysts
- Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of E dispar
- If positive it suggests the diagnosis of amoebiasis.
- Cysts must be differentiated from Entamoeba hartmanni, Endolimax nana, and Entamoeba coli.
- Examination for trophozoites
- As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken.
- A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used.
- Trophozoites must be differentiated with neutrophils.
- Findings suggestive of amoebic colitis include:
- Charcot-leyden crystal protein
- Positive test for heme
- A paucity of neutrophils
Stool antigen detection
Blood test for amoebiasis and stool testing for amoebiasis
References
- ↑ Tanyuksel M, Petri WA (2003). "Laboratory diagnosis of amebiasis". Clin Microbiol Rev. 16 (4): 713–29. PMC 207118. PMID 14557296.
- ↑ Blessmann J, Binh HD, Hung DM, Tannich E, Burchard G (2003). "Treatment of amoebic liver abscess with metronidazole alone or in combination with ultrasound-guided needle aspiration: a comparative, prospective and randomized study". Trop Med Int Health. 8 (11): 1030–4. PMID 14629771.