Amoebic liver abscess laboratory findings: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Yamuna Kondapally (talk | contribs)
nocaptcha
5,127 edits
Yamuna Kondapally (talk | contribs)
nocaptcha
5,127 edits
Line 8: Line 8:
==Laboratory Findings==
==Laboratory Findings==
Laboratory tests consistent with diagnosis of Amoebic liver abscess include:<ref name="pmid14557296">{{cite journal| author=Tanyuksel M, Petri WA| title=Laboratory diagnosis of amebiasis. | journal=Clin Microbiol Rev | year= 2003 | volume= 16 | issue= 4 | pages= 713-29 | pmid=14557296 | doi= | pmc=207118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14557296  }} </ref>
Laboratory tests consistent with diagnosis of Amoebic liver abscess include:<ref name="pmid14557296">{{cite journal| author=Tanyuksel M, Petri WA| title=Laboratory diagnosis of amebiasis. | journal=Clin Microbiol Rev | year= 2003 | volume= 16 | issue= 4 | pages= 713-29 | pmid=14557296 | doi= | pmc=207118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14557296  }} </ref>
{| class="wikitable"
!Lab Test
!Findings
|-
|'''Complete blood picture'''
|
* Heamoglobin <10g/dl
* Leukocytosis
* Neutrophilia
|-
|'''ESR and CRP'''
|Elevated ESR and C-reactive protein<ref name="pmid14629771">{{cite journal| author=Blessmann J, Binh HD, Hung DM, Tannich E, Burchard G| title=Treatment of amoebic liver abscess with metronidazole alone or in combination with ultrasound-guided needle aspiration: a comparative, prospective and randomized study. | journal=Trop Med Int Health | year= 2003 | volume= 8 | issue= 11 | pages= 1030-4 | pmid=14629771 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14629771  }} </ref>
|-
|'''Liver function tests'''
|Acute infection
* Elevated aspartate aminotransferase
* Normal alkaline phosphatase
Chronic infection
* Elevated aspartate aminotransferase
* Normal alkaline phosphatase
|-
|'''Stool examination'''
|Microscopic stool examination for cysts
* Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of ''[[Entamoeba|E dispar]]''
* If positive it suggests the diagnosis of amoebiasis.
* Cysts must be differentiated from ''[[Entamoeba|Entamoeba hartmanni]]'', ''[[Endolimax nana]]'', and ''[[Entamoeba|Entamoeba coli]]''.
Examination for trophozoites
* As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken.
*A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used.
*Trophozoites must be differentiated with neutrophils.
Findings suggestive of amoebic colitis include:
* Charcot-leyden crystal protein
* Positive test for heme
* A paucity of neutrophils


'''Complete blood picture'''
|-
 
|'''Stool antigen detection'''
*Heamoglobin <10g/dl
|
*Leukocytosis
* Used to differentiate ''[[Entamoeba|E histolytica]]'' from ''[[Entamoeba|E dispar]]''
*Neutrophilia
|-
 
|
'''ESR and CRP'''
|
 
|-
Elevated ESR and C-reactive protein<ref name="pmid14629771">{{cite journal| author=Blessmann J, Binh HD, Hung DM, Tannich E, Burchard G| title=Treatment of amoebic liver abscess with metronidazole alone or in combination with ultrasound-guided needle aspiration: a comparative, prospective and randomized study. | journal=Trop Med Int Health | year= 2003 | volume= 8 | issue= 11 | pages= 1030-4 | pmid=14629771 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14629771  }} </ref>
|
 
|
'''Liver function tests'''
|}
 
*
*Acte infection
:*Elevated aspartate aminotransferase
:*Normal alkaline phosphatase
*Chronic infection
:*Elevated aspartate aminotransferase
:*Elevated alkaline phosphatase
 
'''Stool Examination'''
 
*Microscopic stool examination for cysts
:*Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of ''[[Entamoeba|E dispar]]''
:*If positive it suggests the diagnosis of amoebiasis.
:*Cysts must be differentiated from ''[[Entamoeba|Entamoeba hartmanni]]'', ''[[Endolimax nana]]'', and ''[[Entamoeba|Entamoeba coli]]''.
*Examination for trophozoites
:*As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken.
:*A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used.
:*Trophozoites must be differentiated with neutrophils.
*Findings suggestive of amoebic colitis include:
:*Charcot-leyden crystal protein
:*Positive test for heme
:*A paucity of neutrophils
 
'''Stool antigen detection'''
*Used to differentiate ''[[Entamoeba|E histolytica]]'' from ''[[Entamoeba|E dispar]]''




Revision as of 18:03, 8 February 2017

Liver abscess Main Page

Amoebic liver abscess Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating amoebic liver abscess from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Diagnostic Approach

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Amoebic liver abscess laboratory findings On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Amoebic liver abscess laboratory findings

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Amoebic liver abscess laboratory findings

CDC on Amoebic liver abscess laboratory findings

Amoebic liver abscess laboratory findings in the news

Blogs on Amoebic liver abscess laboratory findings

Directions to Hospitals Treating Type chapter name here

Risk calculators and risk factors for Amoebic liver abscess laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Laboratory Findings

Laboratory tests consistent with diagnosis of Amoebic liver abscess include:[1]

Lab Test Findings
Complete blood picture
  • Heamoglobin <10g/dl
  • Leukocytosis
  • Neutrophilia
ESR and CRP Elevated ESR and C-reactive protein[2]
Liver function tests Acute infection
  • Elevated aspartate aminotransferase
  • Normal alkaline phosphatase

Chronic infection

  • Elevated aspartate aminotransferase
  • Normal alkaline phosphatase
Stool examination Microscopic stool examination for cysts

Examination for trophozoites

  • As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken.
  • A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used.
  • Trophozoites must be differentiated with neutrophils.

Findings suggestive of amoebic colitis include:

  • Charcot-leyden crystal protein
  • Positive test for heme
  • A paucity of neutrophils
Stool antigen detection



Blood test for amoebiasis and stool testing for amoebiasis

References

  1. ↑ Tanyuksel M, Petri WA (2003). "Laboratory diagnosis of amebiasis". Clin Microbiol Rev. 16 (4): 713–29. PMC 207118. PMID 14557296.
  2. ↑ Blessmann J, Binh HD, Hung DM, Tannich E, Burchard G (2003). "Treatment of amoebic liver abscess with metronidazole alone or in combination with ultrasound-guided needle aspiration: a comparative, prospective and randomized study". Trop Med Int Health. 8 (11): 1030–4. PMID 14629771.
Retrieved from "https://www.wikidoc.org/index.php?title=Amoebic_liver_abscess_laboratory_findings&oldid=1292012"