Amoebic liver abscess laboratory findings: Difference between revisions

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Revision as of 19:44, 8 February 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S [2]

Laboratory tests consistent with diagnosis of Amoebic liver abscess include:^[1]

Lab Test	Findings
Complete blood picture	Heamoglobin <10g/dl Leukocytosis Neutrophilia
ESR and CRP	Elevated ESR and C-reactive protein^[2]
Liver function tests	Acute infection Elevated aspartate aminotransferase Normal alkaline phosphatase Chronic infection Elevated aspartate aminotransferase Normal alkaline phosphatase
Stool examination	Microscopic stool examination for cysts Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of E dispar^[3] If positive it suggests the diagnosis of amoebiasis. Cysts must be differentiated from Entamoeba hartmanni, Endolimax nana, and Entamoeba coli. Examination for trophozoites As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken. A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used. Trophozoites must be differentiated with neutrophils. Findings suggestive of amoebic colitis include: Charcot-leyden crystal protein Positive test for heme A paucity of neutrophils
Stool antigen detection	Used to differentiate E histolytica from E dispar

Blood test for amoebiasis and stool testing for amoebiasis

@@ Line 31: / Line 31: @@
 |'''Stool examination'''
 |Microscopic stool examination for cysts
-* Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of ''[[Entamoeba|E dispar]]''
+* Microscopic stool examination for cysts is of little value due to infection with nonpathogenic strain of ''[[Entamoeba|E dispar]]''<ref name="pmid7803646">{{cite journal| author=Johnson JL, Baird JS, Hulbert TV, Opas LM| title=Amebic liver abscess in infancy: case report and review. | journal=Clin Infect Dis | year= 1994 | volume= 19 | issue= 4 | pages= 765-7 | pmid=7803646 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7803646  }} </ref>
 * If positive it suggests the diagnosis of amoebiasis.
 * Cysts must be differentiated from ''[[Entamoeba|Entamoeba hartmanni]]'', ''[[Endolimax nana]]'', and ''[[Entamoeba|Entamoeba coli]]''.