Toxic shock syndrome screening: Difference between revisions
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{{Toxic shock syndrome}} | {{Toxic shock syndrome}} | ||
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==Overview== | ==Overview== | ||
Revision as of 18:30, 22 May 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Mainstay of screening for toxic shock syndrome (TSS) is patient education and awareness of the symptoms. Other tests which can be used as a tool to detect the toxic shock syndrome toxin 1 (TSST-1) in patient's blood include the latex agglutination method, and competitive agglutination inhibition assay.
Screening
- Patient education remains a primary key to screening and prevention. Patients should be aware of the symptoms of toxic shock syndrome and, if symptoms occur, they should seek medical attention immediately. [1]
- Latex agglutination method, in which latex particles are sensitized with specific anti-toxic shock syndrome toxin-1 (TSST-1) immunoglobulin, has been found to be a simple and sensitive method for the detection of TSST-1 production by Staphylococcus aureus strains. [2] In order order to exclude other diseases with similar presentation, additional mandatory exclusionary laboratory data needs to be collected.
- Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay has been found to be a preliminary investigation for medical screening of suspected toxic shock syndrome and is applicable in situations where antibody assays are not routinely used for anti-TSST-1 and also where advanced medical equipment is not available.[3]
References
- ↑ Colbry SL (1992). "A review of toxic shock syndrome: the need for education still exists". Nurse Pract. 17 (9): 39–40, 43, 46. PMID 1328970.
- ↑ Igarashi H, Fujikawa H, Shingaki M, Bergdoll MS (1986). "Latex agglutination test for staphylococcal toxic shock syndrome toxin 1". J. Clin. Microbiol. 23 (3): 509–12. PMC 268684. PMID 3082921.
- ↑ Javid Khojasteh V, Rogan MT, Edwards-Jones V, Foster HA (2003). "Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay". Lett. Appl. Microbiol. 36 (6): 372–6. PMID 12753244.