|
|
Line 4: |
Line 4: |
|
| |
|
| ==Overview== | | ==Overview== |
| The [[Institute of Medicine]] (IOM) classified vitamin D deficiency into two groups of deficient and inadequate based on serum 25(OH)D level. Australian Family Physician classified vitamin D deficiency into three groups of mild, moderate and severe. It may be classified into two main groups of acquired or inherited based on the etiology.
| |
|
| |
|
| ==Classification==
| |
| The [[Institute of Medicine]] (IOM) classified vitamin D deficiency into two groups of deficient and inadequate based on serum 25(OH)D level. <ref>Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Ross AC, Taylor CL, Yaktine AL, et al., editors. Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US); 2011. Available from: https://www.ncbi.nlm.nih.gov/books/NBK56070/ doi: 10.17226/13050</ref>
| |
| {| class="wikitable"
| |
| |+ Serum 25(OH)D Concentrations and Health* <ref name="urlVitamin D — Health Professional Fact Sheet">{{cite web |url=https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/#en1 |title=Vitamin D — Health Professional Fact Sheet |format= |work= |accessdate=}}</ref>
| |
| ! style="font-weight: bold;" | nmol/L**
| |
| ! style="font-weight: bold;" | ng/mL*
| |
| ! style="font-weight: bold;" | Health status
| |
| |-
| |
| | <30
| |
| | <12
| |
| | Associated with vitamin D deficiency, leading to rickets in infants and children and osteomalacia in adults
| |
| |-
| |
| | 30 to <50
| |
| | 12 to <20
| |
| | Generally considered inadequate for bone and overall health in healthy individuals
| |
| |-
| |
| | ≥50
| |
| | ≥20
| |
| | Generally considered adequate for bone and overall health in healthy individuals
| |
| |}
| |
|
| |
|
| Australian Family Physician classified vitamin D deficiency into three groups based on serum level of 25(OH)D. <ref name="pmid22708765">{{cite journal |vauthors=Nowson CA, McGrath JJ, Ebeling PR, Haikerwal A, Daly RM, Sanders KM, Seibel MJ, Mason RS |title=Vitamin D and health in adults in Australia and New Zealand: a position statement |journal=Med. J. Aust. |volume=196 |issue=11 |pages=686–7 |year=2012 |pmid=22708765 |doi= |url=}}</ref>
| | ==Pathogenesis== |
|
| |
|
| {| class="wikitable"
| |
| |+ Serum 25(OH)D Concentrations and level of deficiency<ref name="urlRACGP - Vitamin D and the musculoskeletal health of older adults">{{cite web |url=http://www.racgp.org.au/afp/2012/march/vitamin-d-and-the-musculoskeletal-health-of-older-adults/#2 |title=RACGP - Vitamin D and the musculoskeletal health of older adults |journal=Australian Family Physician |volume=41 |issue=3 |pages=92-99 |year=2012}}</ref>
| |
| |-
| |
| | style="font-weight: bold;" | nmol/L**
| |
| | style="font-weight: bold; width:350px"| Level of deficiency
| |
| |-
| |
| | <12.5
| |
| | Severe
| |
| |-
| |
| | 12.5–29
| |
| | Moderate
| |
| |-
| |
| | 30–50
| |
| | Mild
| |
| |}
| |
|
| |
|
| Vitamin D deficiency may be classified into two main groups of acquired or inherited based on the etiology.
| | ==Genetics== |
| | |
| | |
| | ==Associated Conditions== |
|
| |
|
|
| |
|
| ==References== | | ==References== |
| {{Reflist|2}} | | {{reflist|2}} |
|
| |
|
| [[Category:Disease]] | | [[Category:Disease]] |