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Clinically, it can affect multiple organ systems including the heart, skin, joints, kidneys and nervous system.
Clinically, it can affect multiple organ systems including the heart, skin, joints, kidneys and nervous system.


==Classification==  
==Classification==
: [Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
: OR
: [Disease name] may be classified into [Large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
: OR
: [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
: OR
: [Disease name] may be classified into acute and chronic forms, depending on the timing of presentation and duration.


There are several types of lupus; in general, when the word lupus alone is used, reference is to systemic lupus erythematosus, as discussed in this article. Other types include:<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. Chapter 8. ISBN 0721629210.</ref>
Systemic lupus erythematosus, or SLE, is the most common form of lupus.
 
Discoid lupus erythematosus causes a skin rash that doesn't go away.
 
Subacute cutaneous lupus erythematosus causes skin sores on areas of the body exposed to the sun.
 
Neonatal lupus affects newborns.
 
Drug-induced lupus can be caused by certain medicines.
 
There are several types of lupus; in general, when the word lupus alone is used, reference is to systemic lupus erythematosus. different manifestion  Other types include:<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. Chapter 8. ISBN 0721629210.</ref>


*Chronic cutaneous lupus erythematosus
*Chronic cutaneous lupus erythematosus
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*[[Lupus nephritis]], an inflammation of the [[kidney]]s caused by SLE
*[[Lupus nephritis]], an inflammation of the [[kidney]]s caused by SLE
*Complement deficiency syndromes
*Complement deficiency syndromes
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==Diagnosis==
==Diagnosis==

Revision as of 19:46, 23 June 2017

Systemic lupus erythematosus Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Systemic lupus erythematosus from other Diseases

Epidemiology and Demographics

Risk Factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Kiran Singh, M.D. [3]

Overview

Lupus is a chronic autoimmune disease in which the body's own defense system attacks otherwise healthy tissue. Clinically, it can affect multiple organ systems including the heart, skin, joints, kidneys and nervous system.

Classification

[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
OR
[Disease name] may be classified into [Large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
OR
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
OR
[Disease name] may be classified into acute and chronic forms, depending on the timing of presentation and duration.

Systemic lupus erythematosus, or SLE, is the most common form of lupus.

Discoid lupus erythematosus causes a skin rash that doesn't go away.

Subacute cutaneous lupus erythematosus causes skin sores on areas of the body exposed to the sun.

Neonatal lupus affects newborns.

Drug-induced lupus can be caused by certain medicines.

There are several types of lupus; in general, when the word lupus alone is used, reference is to systemic lupus erythematosus. different manifestion Other types include:[1]

  • Chronic cutaneous lupus erythematosus
    • Discoid lupus erythematosus, a skin disorder that causes a red, raised rash on the face and scalp. Discoid lupus occasionally (1–5%) develops into SLE.[2]
      • Localized discoid lupus erythematosus
      • Generalized discoid lupus erythematosus
      • Childhood discoid lupus erythematosus
    • Chilblain lupus erythematosus (Hutchinson)
    • Lupus erythematosus-lichen planus overlap syndrome
    • Lupus erythematosus panniculitis (Lupus erythematosus profundus)
    • Subacute cutaneous lupus erythematosus, which causes nonscarring skin lesions on patches of skin exposed to sunlight.[3]
    • Tumid lupus erythematosus
    • Verrucous lupus erythematosus (Hypertrophic lupus erythematosus)
  • Neonatal lupus erythematosus, a rare disease affecting babies born to women with SLE, Sjögren's syndrome, or sometimes no autoimmune disorder. It is theorized that maternal antibodies attack the fetus, causing skin rash; liver problems; low blood counts, which gradually fade; and heart block, leading to bradycardia.[3]
  • Childhood systemic lupus erythematosus, the pediatric variant of systemic lupus erythematosus.
  • Drug-induced lupus erythematosus, a drug-induced form of SLE; this type of lupus can occur equally in either gender.
  • Lupus nephritis, an inflammation of the kidneys caused by SLE
  • Complement deficiency syndromes

Diagnosis

Physical Examination

Skin

Lupus Erythematosus Chronicus Disseminatus Superficialis
Face
Trunk
Extremity
Lupus Erythematosus Chronicus Verrrucous
Extremity


Trunk
Lupus Erythematosus Profundus
Extremity
Subacute Cutaneous Lupus Erythematosus
Face
Head
Trunk
Systemic Lupus Erythematosus
Face

References

  1. ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Chapter 8. ISBN 0721629210.
  2. ↑ Discoid Lupus Erythematosus
  3. ↑ 3.0 3.1 "Handout on Health: Systemic Lupus Erythematosus". The National Institute of Arthritis and Musculoskeletal and Skin Diseases. National Institutes of Health. 2003. Retrieved 2007-11-23. Unknown parameter |month= ignored (help)
  4. ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 4.20 4.21 4.22 4.23 4.24 4.25 4.26 4.27 4.28 4.29 4.30 4.31 4.32 "Dermatology Atlas".

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